Morphological Comparison of Astrocytes in the Lamina Cribrosa and Glial Lamina. [PDF]
Invest Ophthalmol Vis SciAbstract Purpose Although the mechanisms underlying glaucomatous neurodegeneration are not yet well understood, cellular and small animal models suggest that LC astrocytes undergo early morphologic and functional changes, indicating their role as early responders to glaucomatous ...
Waxman S +4 more
europepmc +4 more sources
Lamina Cribrosa in Glaucoma: Diagnosis and Monitoring [PDF]
Current Ophthalmology Reports, 2015 The lamina cribrosa is the putative site of retinal ganglion cell axonal injury in glaucoma. Although histological studies have provided evidence of structural changes to the lamina cribrosa, even in early stages of glaucoma, until recently, the ability to evaluate the lamina cribrosa in vivo has been limited.
Carolina P B Gracitelli +2 more
exaly +3 more sources
Lamina cribrosa curvature depth and index as novel parameters in Graves’ ophthalmopathy [PDF]
Scientific ReportsThis study aims to evaluate lamina cribrosa (LC) parameters, macular ganglion cell layer thickness (GCLT) and peripapillary retina nerve fiber layer thickness (RNFLT) in Graves’ Ophthalmopathy (GO) patients using spectral domain optical coherence ...
Abdullah Ergen, Büşra Yılmaz Tuğan
doaj +2 more sources
Lamina Cribrosa Steepness Index to Measure the Morphology of the Lamina Cribrosa in Myopic Eyes With Optic Disc Distortion. [PDF]
Transl Vis Sci TechnolTo propose a new parameter for evaluating lamina cribrosa (LC) morphology in myopic eyes with optic nerve head (ONH) distortion.This study included 169 eyes with normal-tension glaucoma (NTG) and myopic ONH distortion from the Myopic NTG Treatment Study.
Lee EJ +13 more
europepmc +3 more sources
Hemodialysis-induced positional changes in lamina cribrosa [PDF]
Scientific ReportsThis study is aimed to investigate the effect of hemodialysis (HD) on the lamina cribrosa (LC) of the optic nerve head (ONH) using swept-source optical coherence tomography (SS-OCT) and other ophthalmological parameters in patients with end-stage kidney ...
Ji Hong Kim +3 more
doaj +2 more sources
CREB3L1 Modulates Extracellular Matrix Gene Expression and Proliferation in Glaucomatous Lamina Cribrosa Cells [PDF]
BiomedicinesBackground: Fibrotic remodelling of the lamina cribrosa (LC) is a defining pathological feature of glaucomatous optic neuropathy and contributes to progressive optic nerve head deformation and axonal vulnerability.
Mustapha Irnaten +3 more
doaj +2 more sources
Nasal and temporal curvatures of lamina CRIBROSA in myopic eyes [PDF]
Scientific Reports, 2022 Little is known about the myopic characteristics of lamina cribrosa (LC) curvature. As such, we investigated nasal and temporal LC curvatures in myopia.
Sooyeon Choe +6 more
doaj +2 more sources
Aquaporin 4 is not present in normal porcine and human lamina cribrosa [PDF]
PLoS ONE, 2022 Aquaporin 4 is absent from astrocytes in the rodent optic nerve head, despite high expression in the retina and myelinated optic nerve. The purpose of this study was to quantify regional aquaporin channel expression in astrocytes of the porcine and human
Elizabeth C. Kimball +7 more
doaj +3 more sources
Study on the deformations of the lamina cribrosa during glaucoma [PDF]
Acta Biomaterialia, 2017 The lamina cribrosa is the primary site of optic nerve injury during glaucoma, and its deformations induced by elevated intraocular pressure are associated directly with the optic nerve injury and visual field defect. However, the deformations in a living body have been poorly understood yet so far.
Fan Song, Long Li
exaly +3 more sources
Defects of the Lamina Cribrosa in High Myopia and Glaucoma. [PDF]
PLoS ONE, 2015 We evaluated the prevalence and characteristics of the defects of the lamina cribrosa (LC) in high myopia and glaucoma, and compared them with control eyes using swept-source optical coherence tomography (SS-OCT).One hundred fifty-nine eyes of 108 ...
Atsuya Miki +4 more
doaj +4 more sources