Results 11 to 20 of about 142,195 (126)

Biomechanical research into lamina cribrosa in glaucoma

open access: yesNational Science Review, 2020
Summary Glaucoma, a leading cause of irreversible blindness, poses a considerable public health challenge and burden. Mechanical models of the lamina cribrosa under elevated intraocular pressure at different scales, contributing significantly to ...
Long Li, F. Song
semanticscholar   +3 more sources

Morphologic Changes in the Lamina Cribrosa Upon Intraocular Pressure Lowering in Patients With Normal Tension Glaucoma

open access: yesInvestigative Ophthalmology and Visual Science, 2022
Purpose The purpose of this study was to investigate whether the lamina cribrosa (LC) curve changes in response to intraocular pressure (IOP) reduction following administration of topical ocular hypotensive eye drops in eyes with normal tension glaucoma (
Jeong-Ah Kim   +6 more
semanticscholar   +1 more source

Deep learning-based 3D OCT imaging for detection of lamina cribrosa defects in eyes with high myopia

open access: yesScientific Reports, 2022
The lamina cribrosa (LC) is a collagenous tissue located in the optic nerve head, and its dissection is observed in eyes with pathologic myopia as a LC defect (LCD).
Mako Ota-Itadani   +5 more
semanticscholar   +1 more source

Comparing Acute IOP-Induced Lamina Cribrosa Deformations Premortem and Postmortem

open access: yesbioRxiv, 2022
Purpose Lamina cribrosa (LC) deformations caused by elevated intraocular pressure (IOP) are believed to contribute to glaucomatous neuropathy and have therefore been extensively studied, in many conditions from in-vivo to ex-vivo.
Junchao Wei   +11 more
semanticscholar   +1 more source

Examination of lamina cribrosa in glaucoma

open access: yesPOINT OF VIEW EAST – WEST, 2022
The main damage in glaucoma starts at the level of the sclera, where the axons of the retinal ganglion cells forming the optic nerve fibers and retinal vessels pass through a network of connective tissue called the lamina cribrosa (LC). Modern diagnostic
N. I. Kuryshevа, V. Kim
semanticscholar   +1 more source

Lamina cribrosa vessel and collagen beam networks are distinct

open access: yesbioRxiv, 2021
Our goal was to analyze the spatial interrelation between vascular and collagen networks in the lamina cribrosa (LC). Specifically, we quantified the percentages of collagen beams with/without vessels and of vessels inside/outside of collagen beams.
S. Waxman   +10 more
semanticscholar   +1 more source

Associating the biomarkers of ocular blood flow with lamina cribrosa parameters in normotensive glaucoma suspects. Comparison to glaucoma patients and healthy controls

open access: yesPLoS ONE, 2021
Purpose To evaluate association between ocular blood flow biomarkers and lamina cribrosa parameters in normotensive glaucoma suspects compared to glaucoma patients and healthy controls.
P. Krzyżanowska-Berkowska   +2 more
semanticscholar   +1 more source

The influence of different intraocular pressure on lamina cribrosa parameters in glaucoma and the relation clinical implication

open access: yesScientific Reports, 2021
Elevated intraocular pressure (IOP) is one of the main risk factors for glaucoma, and pathological changes in the lamina cribrosa (LC) may play a leading role.
Jian Wu   +5 more
semanticscholar   +1 more source

Offset of openings in optic nerve head canal at level of Bruch’s membrane, anterior sclera, and lamina cribrosa

open access: yesScientific Reports, 2021
We compared the central retinal vascular trunk (CRVT) position, as a surrogate of lamina cribrosa (LC) offset, with the anterior scleral opening (ASCO) offset from the Bruch’s membrane opening (BMO).
K. Lee   +4 more
semanticscholar   +1 more source

Optical Coherence Tomography Imaging of the Lamina Cribrosa: Structural Biomarkers in Nonglaucomatous Diseases

open access: yesJournal of Ophthalmology, 2021
The lamina cribrosa (LC) is an active structure that responds to the strain by changing its morphology. Abnormal changes in LC morphology are usually associated with, and indicative of, certain pathologies such as glaucoma, intraocular hypertension, and ...
Alice Paulo   +9 more
semanticscholar   +1 more source

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