Results 21 to 30 of about 5,309 (175)

Biomechanical research into lamina cribrosa in glaucoma

National Science Review, 2020
Summary Glaucoma, a leading cause of irreversible blindness, poses a considerable public health challenge and burden. Mechanical models of the lamina cribrosa under elevated intraocular pressure at different scales, contributing significantly to uncovering the glaucomatous pathogenesis, are discussed.
Li, Long, Song, Fan
openaire   +2 more sources

Axon deviation in the human lamina cribrosa [PDF]

British Journal of Ophthalmology, 1998
To examine the course taken by individual retinal ganglion cell axons through the human lamina cribrosa.Retinal ganglion cell axons were labelled using the retrograde tracer horseradish peroxidase applied directly to the optic nerve in two normal human eyes removed during the course of treatment for extraocular disease.A majority of axons took a direct
J E, Morgan, G, Jeffery, A J, Foss
openaire   +2 more sources

Changes in the lamina cribrosa in patient groups differing in severity of diabetic polyneuropathy

Journal of Ophthalmology, 2018
Background: To our knowledge, no clinical study has previously been performed to investigate morphometric changes in the lamina cribrosa in diabetes mellitus (DM) patients differing in severity of diabetic polyneuropathy (DPN).
M.A. Karliychuk, P.A. Bezditko
doaj   +1 more source

Morphological features of the lamina cribrosa in patients with various degrees of myopia

Journal of Ophthalmology, 2020
Background: The lamina cribrosa plays an important role in the development of vision and undergoes changes as myopia evolves. Purpose: To examine morphological features of the lamina cribrosa in high, moderate and low myopes vs generally healthy ...
P.A. Bezditko, A.O. Gulida
doaj   +1 more source

Tortuous Pore Path Through the Glaucomatous Lamina Cribrosa

Scientific Reports, 2018
The lamina cribrosa is a primary site of damage in glaucoma. While mechanical distortion is hypothesized to cause reduction of axoplasmic flow, little is known about how the pores, which contains the retinal ganglion cell axons, traverse the lamina ...
Bo Wang, Katie A. Lucy, Joel S. Schuman, Ian A. Sigal, Richard A. Bilonick, Chen Lu, Jonathan Liu, Ireneusz Grulkowski, Zachary Nadler, Hiroshi Ishikawa, Larry Kagemann, James G. Fujimoto, Gadi Wollstein   +12 more
doaj   +1 more source

Evaluation of the lamina cribrosa morphology in correlation to retinal nerve fiber layer thickness

Delta Journal of Ophthalmology, 2017
Aim The aim of this study was to assess the correlation between lamina cribrosa (LC) morphology and glaucoma severity using spectral domain optical coherence tomography.
Ayser Abd El-Hameed Fayed
doaj   +1 more source

Lamina cribrosa thickness in children with hyperopic anisometropic amblyopia [PDF]

International Journal of Ophthalmology, 2018
AIM: To determine lamina cribrosa thickness (LCT) in the optic nerve head region of the eyes in children with hyperopic anisometropic amblyopia and to compare this thickness with that of fellow eyes, hyperopic non-amblyopia, and age-matched controls ...
Serkan Akkaya
doaj   +1 more source

Human Lamina Cribrosa Insertion and Age [PDF]

Investigative Opthalmology & Visual Science, 2012
To test the hypothesis that in healthy human eyes the lamina cribrosa (LC) insertion into the pia mater increases with age.The optic nerve heads (ONHs) of donor eyes fixed at either 5 or 50 mm Hg of IOP were sectioned, stained, and imaged under bright- and dark-field conditions. A 3-dimensional (3D) model of each ONH was reconstructed.
Ian A, Sigal, John G, Flanagan, Kira L, Lathrop, Inka, Tertinegg, Richard, Bilonick   +4 more
openaire   +2 more sources

Optic disc microvasculature dropout in primary open-angle glaucoma measured with optical coherence tomography angiography. [PDF]

PLoS ONE, 2018
PURPOSE:To evaluate microvasculature dropout in the optic disc (Mvd-D) using optical coherence tomography angiography (OCTA) and investigate factors associated with Mvd-D in primary open-angle glaucoma (POAG) eyes.
Tadamichi Akagi, Linda M Zangwill, Takuhei Shoji, Min Hee Suh, Luke J Saunders, Adeleh Yarmohammadi, Patricia Isabel C Manalastas, Rafaella C Penteado, Robert N Weinreb   +8 more
doaj   +1 more source

Circumpapillary retinal nerve fiber layer thickness, anterior lamina cribrosa depth, and lamina cribrosa thickness in neovascular glaucoma secondary to proliferative diabetic retinopathy: a cross-sectional study

BMC Ophthalmology, 2017
Background To compare the lamina cribrosa between eyes with and without neovascular glaucoma (NVG) using enhanced depth imaging spectral-domain optical coherence tomography. Methods Forty-six patients with proliferative diabetic retinopathy were enrolled
Satoshi Yokota, Yuji Takihara, Yoshihiro Takamura, Masaru Inatani   +3 more
doaj   +1 more source