Results 211 to 220 of about 221,211 (337)

A Closed‐Loop‐Capable Neural Interface Platform for Deep Brain Modulation via Integrated Non‐Viral Gene Delivery, NIR Optogenetics, and Electrophysiological Recording

Advanced Science, EarlyView.
A multifunctional, 3D porous neural interface combines non‐viral gene delivery and NIR optogenetics to enable minimally invasive, closed‐loop modulation of deep‐brain circuits. Abstract Closed‐loop neuromodulation requires precise, stable, and cell‐specific control of neural circuits with minimal invasiveness.
Chao‐Yi Chu, Zih‐Huei Chen, Chun‐Wei Liang, Pu‐Wei Wu, Wei‐Qing Guo, Bo‐Wei Chen, Chih‐Chia Huang, Ssu‐Ju Li, Ching‐Wen Chang, Yao‐Wen Liang, Shun‐An Kan, Yu‐Chun Lo, Wei‐Chen Huang, You‐Yin Chen, San‐Yuan Chen   +14 more
wiley   +1 more source

<i>LAMA2</i> variants associated with muscular dystrophy, brain structural abnormalities, and epilepsy: a genotype-phenotype study. [PDF]

Front Neurol
Zha J, Yu Y, Cao F, Yi Z, Wu H, Chen Y, Zhong J, Yu X.   +7 more
europepmc   +1 more source

Utility of the laminin immunohistochemical stain in distinguishing invasive from noninvasive urothelial carcinoma

, 2017
Dinesh Pradhan, Milon Amin, Shveta Hooda, Rajiv Dhir, Sheldon Bastacky, Anil V. Parwani   +5 more
openalex   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

Laminin N-terminus α31 regulates corneal epithelial cell adhesion and migration through modifying the organization and proteolytic processing of laminin 332. [PDF]

PLoS One
Troughton LD, Iorio V, Shaw L, Sugden CJ, Chavda ND, Wilson P, Simoens D, Conway AE, Sala S, Kaja S, Yamamoto K, Hamill KJ.   +11 more
europepmc   +1 more source

Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor.

, 1992
Alan D. Murdoch, George R. Dodge, I. Cohen, Rocky S. Tuan, Renato V. Iozzo   +4 more
openalex   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source

Enamel Defects in Carriers of a Novel LAMA3 Mutation Underlying Epidermolysis Bullosa [PDF]

, 2012
Jonkman, MF, Pasmooij, AM, Stellingsma, C, Yuen, WY   +3 more
core   +2 more sources

KANK1 regulates the positioning of liprin-α1 and the spatial organization of insulin granule fusion in pancreatic β cells. [PDF]

J Biol Chem
Deng K, Sun K, Webster H, Yau B, Loudovaris T, Thomas HE, Kebede MA, Thorn P.   +7 more
europepmc   +1 more source

Binding of the α₂Integrin I Domain to Extracellular Matrix Ligands: Structural and Mechanistic Differences between Collagen and Laminin Binding [PDF]

, 1998
S. Kent Dickeson, John J. Walsh, Samuel A. Santoro   +2 more
openalex   +1 more source