Results 231 to 240 of about 178,658 (287)

Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche. [PDF]

Elife
Masson C, Scandola C, Rinckel JY, Proamer F, Janus-Bell E, Batool F, Osmani N, Goetz JG, Mallo L, Brouard N, Leon C, Bornert A, Poincloux R, Destaing O, Mansson A, Qian H, Lehmann M, Eckly A.   +17 more
europepmc   +1 more source

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

Environmental Toxicology, EarlyView.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo, Patricia Meade, Irene Jiménez‐Salvador, Carmen Hernández‐Ainsa, Eldris Iglesias, Alba Pesini, Nuria Garrido‐Pérez, Sonia Emperador, David Pacheu‐Grau, Pilar Bayona‐Bafaluy, Eduardo Ruiz‐Pesini   +10 more
wiley   +1 more source

Pericytes repair engineered defects in the basement membrane to restore barrier integrity in an <i>in vitro</i> model of the blood-brain barrier. [PDF]

Mater Today Bio
Trempel MA, Du Y, Widom LP, Reitz EE, Feidler AM, Kasap P, Engelhardt B, Gaborski TR, Gelbard HA, Terrando N, McGrath JL.   +10 more
europepmc   +1 more source

ChitoSilkBioPatch: A bio‐inspired wound dressing scaffold for antibiotic‐free diabetic wound management

VIEW, EarlyView.
We present ChitoSilkBioPatch, a maleimide‐functionalized chitosan/dACM hydrogel integrated with a stretchable nanopatterned silk mesh to provide intrinsic, antibiotic‐free antibacterial activity and bioactive wound support. The scaffold eliminates S. aureus and P.
Dorsa Dehghan‐Baniani, Babak Mehrjou, Yucong Li, Zhaowei Jiang, Xiaomin Lu, Yin Xiao, Huanxiong Chen, Tsz Lam Yiu, Chi Chiu Wang, Hongkai Wu, Gang Li, Paul K. Chu, Wayne Yuk Wai Lee   +12 more
wiley   +1 more source

Epidermal stem cells control periderm injury repair via matrix-driven specialization of intercellular junctions. [PDF]

Nat Commun
He HM, Boraas LC, Bell JM, Gong X, Iannaccone SL, Wen Z, Mak M, Carlson M, Sumigray K, Nicoli S.   +9 more
europepmc   +1 more source

Comprehensive analysis and functional validation of key genes in bladder cancer progression

VIEW, EarlyView.
Bladder cancer is highly diverse between patients, making it difficult to accurately predict who will have aggressive disease and poor outcomes. In this study, we integrated single‐cell RNA sequencing with clinical survival data to identify a simple three‐gene signature (FAM3B, C10orf99, and VMP1) that stratifies patients into high‐ and low‐risk groups.
Xiaoning Cheng, Hongxia Zhao, Qian Li, Boyang Liu, Maoping Cai, Xinyi Wang, Jiancong Lie, Yuanyuan Qu, Jianwei Li, Chunlong Yang   +9 more
wiley   +1 more source

Modeling functional responses to pollutant exposure using modular hydrogel supported vascularized alveolosphere-on-a-chip.

Biomater Sci
Madhurakkat Perikamana SK, Kumar V, Mogha P, Duncan L, Angel N, Tata A, Jabba SV, Jordt SE, Tata PR, Varghese S.   +9 more
europepmc   +1 more source

Development of a 3D tumor model based on decellularized matrix using high-throughput approaches. [PDF]

Front Bioeng Biotechnol
Siahmansouri H, Fenoglio D, Filaci G, Mastrogiacomo M.   +3 more
europepmc   +1 more source

Three‐dimensional patient‐derived endometriosis model for drug evaluation

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this study, we developed a coculturing model with stromal cells and epithelial organoids to mimic the endometriotic lesion and for further evaluation of drug effects. Abstract Introduction Endometriomsis (EMs) is a complex and chronic gynecological disease characterized by distressing symptoms.
Yuqi Li, Wei Shao, Xiaoxiao Gao, Yongxing Wang, Jinzhi Li, Liansuo Zhang, Yanyan Xing, Wentao Su, Yan Cheng, Li Wang, Songping Liu   +10 more
wiley   +1 more source

Exploring the Role of the Extracellular Matrix in Disease and Aging. [PDF]

Juntendo Med J
Arikawa-Hirasawa E.
europepmc   +1 more source