Results 51 to 60 of about 174,268 (199)
Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development [PDF]
Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices in alveogenesis is not fully understood, because prior knowledge is largely extrapolated from ...
Chen, Hui+9 more
core +2 more sources
Review: Dystroglycan in the Nervous System [PDF]
Dystroglycan is part of a large complex of proteins, the dystrophin-glycoprotein complex, which has been implicated in the pathogenesis of muscular dystrophies for a long time.
Matthias Samwald
core +2 more sources
A biomimetic kidney tubule model [PDF]
A critical barrier in the nephrology field is the lack of appropriate in vitro renal tubule models that allow manipulation of various mechanical factors, facilitating studies of disease pathophysiology and drug discovery. Here we report development of a novel in vitro assay system comprised of a renal tubule within an elasto-plastic extracellular ...
arxiv
Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]
Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Hodgson, Lorna+3 more
core +2 more sources
Further biochemical characterization of Mycobacterium leprae laminin-binding proteins
It has been demonstrated that the alpha2 chain of laminin-2 present on the surface of Schwann cells is involved in the process of attachment of Mycobacterium leprae to these cells. Searching for M. leprae laminin-binding molecules, in a previous study we
M.A.M. Marques+6 more
doaj +1 more source
A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]
Background: The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Fox, Michael A.+3 more
core +3 more sources
Objectives: Oral squamous cell carcinoma is associated with alterations in basement membrane. Laminin-332 is present in basal lamina and performs multiple biologic effects by γ2 chain. Matrix metalloproteinase acts disrupting extracellular components and
Eline Manhães Reid Silva+4 more
doaj +1 more source
Cranial and trunk neural crest cells use different mechanisms for attachment to extracellular matrices [PDF]
We have used a quantitative cell attachment assay to compare the interactions of cranial and trunk neural crest cells with the extracellular matrix (ECM) molecules fibronectin, laminin and collagen types I and IV.
Artinger, Kristin B.+3 more
core
Distinct morphologies of fusion and closure of the choroid fissure [PDF]
Coloboma is a disorder characterized by the lack of fusion of the embryonic choroid fissure, a transient cleft along the ventral midline of the eye.
Anderson, Mitch
core +1 more source
Status epilepticus (SE, a prolonged seizure activity) impairs brain-blood barrier (BBB) integrity, which results in secondary complications following SE.
Hana Park+7 more
doaj +1 more source