Results 51 to 60 of about 174,268 (199)

Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development [PDF]

open access: yes, 2018
Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices in alveogenesis is not fully understood, because prior knowledge is largely extrapolated from ...
Chen, Hui   +9 more
core   +2 more sources

Review: Dystroglycan in the Nervous System [PDF]

open access: yes, 2007
Dystroglycan is part of a large complex of proteins, the dystrophin-glycoprotein complex, which has been implicated in the pathogenesis of muscular dystrophies for a long time.
Matthias Samwald
core   +2 more sources

A biomimetic kidney tubule model [PDF]

open access: yesarXiv, 2020
A critical barrier in the nephrology field is the lack of appropriate in vitro renal tubule models that allow manipulation of various mechanical factors, facilitating studies of disease pathophysiology and drug discovery. Here we report development of a novel in vitro assay system comprised of a renal tubule within an elasto-plastic extracellular ...
arxiv  

Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]

open access: yes, 2012
Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Hodgson, Lorna   +3 more
core   +2 more sources

Further biochemical characterization of Mycobacterium leprae laminin-binding proteins

open access: yesBrazilian Journal of Medical and Biological Research, 2001
It has been demonstrated that the alpha2 chain of laminin-2 present on the surface of Schwann cells is involved in the process of attachment of Mycobacterium leprae to these cells. Searching for M. leprae laminin-binding molecules, in a previous study we
M.A.M. Marques   +6 more
doaj   +1 more source

A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]

open access: yes, 2008
Background: The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Fox, Michael A.   +3 more
core   +3 more sources

Immunohistochemical Study of Laminin-332 γ2 Chain and MMP-9 in High Risk of Malignant Transformation Oral Lesions and OSCC

open access: yeseJournal of Oral Maxillofacial Research, 2018
Objectives: Oral squamous cell carcinoma is associated with alterations in basement membrane. Laminin-332 is present in basal lamina and performs multiple biologic effects by γ2 chain. Matrix metalloproteinase acts disrupting extracellular components and
Eline Manhães Reid Silva   +4 more
doaj   +1 more source

Cranial and trunk neural crest cells use different mechanisms for attachment to extracellular matrices [PDF]

open access: yes, 1992
We have used a quantitative cell attachment assay to compare the interactions of cranial and trunk neural crest cells with the extracellular matrix (ECM) molecules fibronectin, laminin and collagen types I and IV.
Artinger, Kristin B.   +3 more
core  

Distinct morphologies of fusion and closure of the choroid fissure [PDF]

open access: yes, 2017
Coloboma is a disorder characterized by the lack of fusion of the embryonic choroid fissure, a transient cleft along the ventral midline of the eye.
Anderson, Mitch
core   +1 more source

Dysfunction of 67-kDa Laminin Receptor Disrupts BBB Integrity via Impaired Dystrophin/AQP4 Complex and p38 MAPK/VEGF Activation Following Status Epilepticus

open access: yesFrontiers in Cellular Neuroscience, 2019
Status epilepticus (SE, a prolonged seizure activity) impairs brain-blood barrier (BBB) integrity, which results in secondary complications following SE.
Hana Park   +7 more
doaj   +1 more source

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