CNS Neurons Deposit Laminin α5 to Stabilize Synapses
Cell Reports, 2017 Summary: Synapses in the developing brain are structurally dynamic but become stable by early adulthood. We demonstrate here that an α5-subunit-containing laminin stabilizes synapses during this developmental transition.
Mitchell H. Omar +7 more
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Tumor Microenvironment-based Gene Signatures Divides Novel Immune and Stromal Subgroup Classification of Lung Adenocarcinoma [PDF]
arXiv, 2019 Tumor microenvironment has complex effects on tumorigenesis and metastasis. However, there is still a lack of comprehensive understanding of the relationship among molecular and cellular characteristics in tumor microenvironment, clinical prognosis and immunotherpy response.
arxiv
The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin. [PDF]
, 1990 This study was undertaken to determine the roles of individual alpha/beta 1 integrin heterodimers in promoting cellular interactions with the different attachment-promoting domains of laminin (LN). To do this, antibodies to the integrin beta 1 subunit or
Crowley, E +6 more
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NC1 Domain of Type VII Collagen Binds to the β3 Chain of Laminin 5 Via a Unique Subdomain Within the Fibronectin-Like Repeats [PDF]
, 1999 Type VII collagen, the major component of anchoring fibrils, consists of a central collagenous triple-helical domain flanked by two noncollagenous, globular domains, NC1 and NC2.
Chen, Mei +5 more
core +1 more source
Memorias do Instituto Oswaldo Cruz, 2015 This study investigated the possible relationship between the invasiveness of group A Streptococcus (GAS) strains and their abilities to adhere to laminin and assessed the effects of subinhibitory concentrations of penicillin and erythromycin on the ...
Aleksandra Šmitran +4 more
doaj +1 more source
Molecular mechanisms separating two axonal pathways during embryonic development of the avian optic tectum [PDF]
, 1991 During embryonic development of the avian optic tectum, retinal and tectobulbar axons form an orthogonal array of nerve processes. Growing axons of both tracts are transiently very closely apposed to each other. Despite this spatial proximity, axons from
Adler +55 more
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Fibronectin and Cyclic Strain Improve Cardiac Progenitor Cell Regenerative Potential In Vitro. [PDF]
, 2016 Cardiac progenitor cells (CPCs) have rapidly advanced to clinical trials, yet little is known regarding their interaction with the microenvironment. Signaling cues present in the microenvironment change with development and disease.
Bhutani, Srishti +8 more
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Interactions of laminin with the amyloid ß peptide: Implications for Alzheimer's disease
Brazilian Journal of Medical and Biological Research, 2001 Extensive neuronal cell loss is observed in Alzheimer's disease. Laminin immunoreactivity colocalizes with senile plaques, the characteristic extracellular histopathological lesions of Alzheimer brain, which consist of the amyloid ß (Aß) peptide ...
Morgan C., Inestrosa N.C.
doaj
IMMUNOMORPHOLOGICAL FEATURES OF IDIOPATHIC EPIRETINAL MEMBRANES COMPLICATED BY LAMELLAR MACULAR HOLE
Oftalʹmologiâ, 2017 Objective: Comparative morphological characteristic and evaluation of cytokine profile of idiopathic epiretinal membrane (ERM), complicated lamellar macular hole.
U. R. Altynbaev, A. I. Lebedeva
doaj +1 more source
Extracellular matrix and integrins influence in the regulation of myogenic precursor cells behaviour [PDF]
, 2009 Tese de mestrado, Biologia (Biologia Molecular Humana), 2009, Universidade de Lisboa, Faculdade de CiênciasMyogenesis is the process by which undifferentiated dermomyotomal cells are specified for myogenesis, move towards the myotome where they ...
Vaz, Raquel Rodrigues
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