Binding properties of Treponema denticola lipooligosaccharide
Journal of Oral Microbiology, 2013 Background and objective: The cell-surface lipooligosaccharide (LOS) of Treponema denticola possesses several biological properties. The aim of this study was to investigate the binding properties of T.
Daniel Grenier
doaj +1 more source
Muscular dystrophy meets protein biochemistry, the mother of invention [PDF]
, 2017 Muscular dystrophies result from a defect in the linkage between the muscle fiber cytoskeleton and the basement membrane (BM). Congenital muscular dystrophy type MDC1A is caused by mutations in laminin α2 that either reduce its expression or impair its ...
Jeffrey H. Miner +3 more
core +2 more sources
Laminin-111-derived peptides and cancer
Cell Adhesion & Migration, 2013 Laminin-111 is a large trimeric basement membrane glycoprotein with many active sites. In particular, four peptides active in tumor malignancy studies have been identified in laminin-111 using a systematic peptide screening method followed by various ...
Y. Kikkawa +5 more
semanticscholar +1 more source
Changes in Laminin Expression Pattern during Early Differentiation of Human Embryonic Stem Cells. [PDF]
PLoS ONE, 2015 Laminin isoforms laminin-511 and -521 are expressed by human embryonic stem cells (hESC) and can be used as a growth matrix to culture these cells under pluripotent conditions.
Martin Pook +5 more
doaj +1 more source
Binding between the neural cell adhesion molecules axonin-1 and Nr- CAM/Bravo is involved in neuron-glia interaction [PDF]
, 1995 Neural cell adhesion molecules of the immunoglobulin superfamily mediate cellular interactions via homophilic binding to identical molecules and heterophilic binding to other family members or structurally unrelated cell-surface glycoproteins.
Buchstaller, Andrea +5 more
core +4 more sources
Further biochemical characterization of Mycobacterium leprae laminin-binding proteins
Brazilian Journal of Medical and Biological Research, 2001 It has been demonstrated that the alpha2 chain of laminin-2 present on the surface of Schwann cells is involved in the process of attachment of Mycobacterium leprae to these cells. Searching for M. leprae laminin-binding molecules, in a previous study we
M.A.M. Marques +6 more
doaj +1 more source
Abnormal Endothelial Gene Expression Associated With Early Coronary Atherosclerosis
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background We examined feasibility of a unique approach towards gaining insight into heritable risk for early atherosclerosis: surveying gene expression by endothelial cells from living subjects. Methods and Results Subjects aged
Robert P. Hebbel +9 more
doaj +1 more source
The association of laminin levels with insulin resistance and non-alcoholic hepatosteatosis
Diabetology & Metabolic Syndrome, 2021 Background Laminin, one of the largest glycoproteins of the basement membrane, is an important component of the extracellular matrix. Functions of the basement membrane include regulation of cell signaling behaviors and structural support.
Özgür Altun +8 more
doaj +1 more source
Experimental Lung Research, 1997 Laminins are essential components of basement membranes, playing important roles in cell adhesion, proliferation, and differentiation. These heterotrimeric glycoproteins are composed of an alpha, beta, and gamma chains held together by disulfide bonds. The first laminin identified, from the mouse Engelbreth-Holm-Swarm (EHS) tumor, is now referred to as
openaire +3 more sources
A novel mutation in isoform 3 of the plasma membrane Ca2+ pump impairs cellular Ca2+ homeostasis in a patient with cerebellar ataxia and laminin subunit 1\u3b1 mutations. [PDF]
, 2015 The particular importance of Ca2+ signaling to neurons demands its precise regulation within their cytoplasm. Isoform 3 of the plasma membrane Ca2+ ATPase (the PMCA3 pump), which is highly expressed in brain and cerebellum, plays an important role in the
Brini, Marisa +9 more
core +1 more source