Results 31 to 40 of about 1,743 (194)
Reciprocated Tachycardias in Cardiac Laminopathy: A Clinical Case Report [PDF]
European Heart Journal - Case ReportsNatalia Sonicheva-Paterson +2 more
exaly +2 more sources
Ventricular Tachycardia Ablation in Structural Heart Disease With LVEF > 35%: Clinical Outcomes and Recurrence Patterns. [PDF]
J Cardiovasc ElectrophysiolABSTRACT Background In patients with structural heart disease (SHD) and moderately impaired left ventricular ejection fraction (LVEF > 35%), data on outcomes after ventricular tachycardia (VT) ablation remain limited. This analysis focuses on VT recurrence after ablation in patients presenting with sustained VT and LVEF > 35% within a secondary ...
Waezsada SE +14 more
europepmc +2 more sources
Laminopathies and Atherosclerosis [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 Laminopathies are genetic diseases that encompass a wide spectrum of phenotypes with diverse tissue pathologies and result mainly from mutations in the LMNA gene encoding nuclear lamin A/C. Some laminopathies affect the cardiovascular system, and a few (namely, Dunnigan-type familial partial lipodystrophy [FPLD2 ...
Khalid Z, Al-Shali, Robert A, Hegele
openaire +2 more sources
Familial cardiac laminopathy with predominant atrial involvement: a case series of a family with <i>LMNA</i> mutation. [PDF]
Eur Heart J Case RepInternational audienceAbstract Background We present a case series detailing a family with familial cardiac laminopathy, including the female index patient, her father, her brother, and her daughter, all diagnosed with atrial arrhythmias, i.e.
Müssigbrodt A +7 more
europepmc +2 more sources
Downregulation of Nesprin1 by Runx2 Deficiency Is Critical for the Development of Skeletal Laminopathy-Like Pathology [PDF]
Proceedings of the National Academy of Sciences of the United States of AmericaToshifumi Azuma +2 more
exaly +2 more sources
IFN-Aging: Coupling Aging With Interferon Response
Frontiers in Aging, 2022 Chronic inflammation affects many diseases and conditions, including aging. Interferons are a part of the immune defense against viral infections. Paradoxically, various aging tissues and organs from mammalian hosts perpetually accumulate changes brought
Wei Cao
doaj +1 more source
Preclinical Advances of Therapies for Laminopathies [PDF]
Journal of Clinical Medicine, 2021 Laminopathies are a group of rare disorders due to mutation in LMNA gene. Depending on the mutation, they may affect striated muscles, adipose tissues, nerves or are multisystemic with various accelerated ageing syndromes. Although the diverse pathomechanisms responsible for laminopathies are not fully understood, several therapeutic approaches have ...
Benarroch, Louise +5 more
openaire +3 more sources
Cells, 2023 Oxidative stress is a physiological condition that arises when there is an imbalance between the production of reactive oxygen species (ROS) and the ability of cells to neutralize them.
Lidya Kristiani, Youngjo Kim
doaj +1 more source
Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts [PDF]
, 2018 Significance The lamin proteins are an important component of the nuclear scaffold. Abnormal lamins can cause a variety of disorders called laminopathies, one of which is the premature aging disorder Hutchinson-Gilford progeria syndrome (HGPS).
Stephen T. Lichtenstein +5 more
core +2 more sources
Phenotypic Scoring of C. elegans Laminopathy Models.
, 2023 Phenotypic Scoring of C. elegans Laminopathy Models.
Ellen F. Gregory (5638820) +6 more
core +1 more source