Results 181 to 190 of about 24,362 (263)

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 1957-1976, July 2026.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway   +24 more
wiley   +1 more source

Postherpetic Neuralgia: Mechanisms, Risk Factors, and Stratified Management—A Narrative Review

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
The incidence of PHN is increasing, posing a substantial public health burden. Its pathogenesis involves VZV reactivation, peripheral and central sensitization, and genetic susceptibility, with key risk factors including older age, severe acute pain, extensive rash, immunocompromise, comorbidities, and delayed treatment.
Fei Tang, Fukun Zhao
wiley   +1 more source

Drug Critical Limits for Urgent Physician Notification

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 178-192, July 2026.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang   +3 more
wiley   +1 more source

Photoinduced granulomatous drug reaction related to lamotrigine. [PDF]

open access: yesJAAD Case Rep
Clerc J, Aubin F, Cretin B, Devalland C.
europepmc   +1 more source

Environmental and Spatial Variables Influencing Contaminants of Emerging Concern in Watersheds Across Central NY

open access: yesHydrological Processes, Volume 40, Issue 7, July 2026.
This manuscript explores empirical linkages between a suite of concentrations of chemicals of emerging concern (CEC) and hydroclimatological and spatial watershed characteristics. Our analysis was carried out at the regional scale allowing us to explore how complex patterns of land use relate to CEC concentrations.
Ruta Basijokaite   +3 more
wiley   +1 more source

Comparison of Large Language Model‐Based Systems and Prompt Engineering for Internal Medicine Clinical Pharmacy Cases

open access: yesJACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 7, July 2026.
ABSTRACT Background Large language models (LLMs) are an application of artificial intelligence and generate responses to user inquiries that vary in accuracy and completeness. Methods of improving LLM response quality are poorly evaluated in the context of clinical pharmacy practice.
Samuel S. Yang   +3 more
wiley   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu   +8 more
wiley   +1 more source

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