Results 111 to 120 of about 1,334,232 (314)
Open-access publication is inarguably valuable to science and to the public, yet skepticism about the long-term sustainability of open-access publications persists (see Nature, October 9, and Science, October 24). While some fear the effects of the open-access model—which shifts revenue streams from subscription fees to publication fees—on scientific ...
Helen Doyle, Andy Gass, Debra Lappin
openaire +4 more sources
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Society, culture and people in landscape research [PDF]
Landscape is a concept which straddles the natural and social sciences, bringing together a variety of physical and cultural elements. This study aims to assess the relative level of importance that physical and cultural landscape elements are ...
25 Years of Landscape Ecology: Scientific Principles in Practice +3 more
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Une marginalité spatiale comme clé de lecture des territoires
Until the end of the XIX century and the phylloxeric episode, vine was one of the principal resources in Haute-Saône. According to agricultural statistics, since the nineteen seventies this culture has officially disappeared from most of the villages of ...
Sylvain Estager
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
“The Landscape of wheat - A landscape of power” pp: 66-70 [PDF]
Portugal in the end of the 19 th century was characterized by a huge economic and political instability. This situation led to the publication of the Hunger Law (1899), which is identified as the critical breaking point since it imposed a political ...
Simões, Paula, Carapinha, Auroa
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ECONOMIC AND FINANCIAL ASPECTS OF ACTIVITY IN SC "AGRO ANCA" SRL, RO.IORII DE VEDE, COUNTY TELEORMAN (2011-2012) [PDF]
The unit was established in 2008, with the object of activity "permanent cultivation of plants" - NACE Code 011 principal activity "Growing of cereals (except rice), leguminous crops and oil seeds plant".
Radu Lucian PÂNZARU +1 more
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
On a landscape approach to design and eco-poetic approach to Landscape [PDF]
For Landscape Architecture to become an academic discipline it must present its own coherent theory and methodology for the planning, designing and management of (built) landscapes.
Koh, J.
core
Shifting shores: Transformative learning with the city
Highlights: – Post-human methodologies support geographical experimentation in social science education – Walking with a virtual (Deleuze) landscape manifests the materiality of the city – Diverse temporal and spatial rhythms reveal the subject as
William Smolander, Raine Aiava
doaj +1 more source

