Results 31 to 40 of about 3,064,611 (299)

The Dynamic Landscapes of RNA Architecture [PDF]

Cell, 2009
A wealth of information on RNA folding and ribonucleoprotein assembly has emerged from analyses of structures and from the use of innovative biophysical tools. Although integrating data obtained from static structures with dynamic measurements presents major challenges, such efforts are opening new vistas on the RNA folding landscape.
Cruz, José Almeida, Westhof, Eric
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

JoLA-Journal of Landscape Architecture [PDF]

, 2013
From the JoLA-Journal of Landscape Architecture web site, http://www.jola-lab.eu/www/about.html: "JoLA is the peer-reviewed academic Journal of Landscape Architecture established by the European Council of Landscape Architecture Schools (ECLAS) in 2006 ...
B., BLANCHON CAILLOT, K., Shannon, K., Gill, K., Joergensen, Rinaldi, BIANCA MARIA   +4 more
core  

PfERF106, a novel key transcription factor regulating the biosynthesis of floral terpenoids in Primula forbesii Franch

BMC Plant Biology
Background Flowers can be a source of essential oils used in the manufacture of substances with high economic value. The ethylene response factor (ERF) gene family plays a key role in regulating secondary metabolite biosynthesis in plants. However, until
Xiancai Yin, Hongchen Yang, Keying Ding, Yuanzhi Luo, Wanqing Deng, Jianwei Liao, Yuanzhi Pan, Beibei Jiang, Xue Yong, Yin Jia   +9 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

JoLA-Journal of Landscape Architecture [PDF]

, 2012
From the JoLA-Journal of Landscape Architecture web site, http://www.jola-lab.eu/www/about.html: "JoLA is the peer-reviewed academic Journal of Landscape Architecture established by the European Council of Landscape Architecture Schools (ECLAS) in 2006 ...
B., BLANCHON CAILLOT, K., Shannon, K., Gill, K., Joergensen, Rinaldi, BIANCA MARIA   +4 more
core  

Optimization of Green Spaces in Plain Urban Areas to Enhance Carbon Sequestration

Land, 2023
Global climate change and rapid urbanization have placed enormous pressure on the urban ecological environment worldwide. Urban green spaces, which are an important component of urban ecosystems, can maintain ecological and environmental sustainability ...
Peiyuan Tao, Ye Lin, Xing Wang, Jiayan Li, Chao Ma, Zhenkun Wang, Xinyue Dong, Peng Yao, Ming Shao   +8 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Mitigating Ni and Cu ecotoxicity in the ecological restoration material and ornamental Primula forbesii Franch. with exogenous 24-epibrassinolide and melatonin

Scientific Reports
Nickel (Ni) and copper (Cu) contamination have become major threats to plant survival worldwide. 24-epibrassinolide (24-EBR) and melatonin (MT) have emerged as valuable treatments to alleviate heavy metal-induced phytotoxicity.
Hongchen Yang, Jian Zhao, Xiancai Yin, Keying Ding, Xinhui Gao, Yuxin Cai, Yuanzhi Pan, Beibei Jiang, Qinglin Liu, Yin Jia   +9 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source