Results 51 to 60 of about 3,098,837 (287)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
On Landscape Architecture Education and Professional Practice and Their Future Challenges
Land, 2020 Increased environmental and social risk, ubiquitous information technology, and growing demands for and growing threats to democracy and public participation will alter the education and practice of all the design professions and the geographically ...
C. Steinitz
semanticscholar +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Scientific ReportsAcer fabri is an excellent color-leaf tree species, with high ornamental value. Low temperatures are known to limit the growth and geographical distribution of A. fabri. The molecular mechanism of A. fabri in response to low-temperature stress was rarely
Gongwei Chen +8 more
doaj +1 more source
Distribution of Landscape Architecture Based on 3D Images and Virtual Reality Rationality Study
IEEE Access, 2020 In order to ensure the rationality of landscape design, it is of great practical significance to simulate the planning effect. Aiming at the problems of traditional garden landscape distribution simulation technology, this paper designs a new garden ...
Ruiyi Li, Dawei Xu
semanticscholar +1 more source
Harmonized single-cell landscape, intercellular crosstalk and tumor architecture of glioblastoma
bioRxiv, 2022 Glioblastoma, isocitrate dehydrogenase (IDH)-wildtype (hereafter, GB), is an aggressive brain malignancy associated with a dismal prognosis and poor quality of life.
C. Ruiz-Moreno +6 more
semanticscholar +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Scientific ReportsNickel (Ni) and copper (Cu) contamination have become major threats to plant survival worldwide. 24-epibrassinolide (24-EBR) and melatonin (MT) have emerged as valuable treatments to alleviate heavy metal-induced phytotoxicity.
Hongchen Yang +9 more
doaj +1 more source
Optimization of Green Spaces in Plain Urban Areas to Enhance Carbon Sequestration
Land, 2023 Global climate change and rapid urbanization have placed enormous pressure on the urban ecological environment worldwide. Urban green spaces, which are an important component of urban ecosystems, can maintain ecological and environmental sustainability ...
Peiyuan Tao +8 more
doaj +1 more source