Results 111 to 120 of about 1,438,311 (284)

Mapping a landscape of learning design: Identifying key trends in current practice at the Open University [PDF]

open access: yes, 2008
The object of this paper is to present some early analysis of interview and focus group data about how existing teacher educators at The Open University (UK) approach, understand, and deploy learning design and the additional support and tools they would
Brasher, Andrew   +4 more
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Enhancing Sustainability by Landscape-Design and Conversion to Organic Agriculture [PDF]

open access: yes, 2005
A hilly site with variable soils and facing all the problems of modern agriculture was re-designed and converted to organic agriculture in 1992. After 10 years of measurements and observations it was determined that soil compaction, runoff, and erosion ...
Kainz, Maximilian
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

The Ideal Strategy of Carbon-Neutral for Park Landscape Design: A Proposal for a Rapid Detection Method

open access: yesApplied Sciences
The primary objective of this study is to investigate the carbon footprint, resilience levels, and optimal landscape area ratios of various parks. Additionally, it explores the relationships between landscape element proportions (LEP), the normalized ...
Shengjung Ou   +4 more
doaj   +1 more source

Urban Landscape Design

open access: yes, 2012
Peyzaj, the Turkish word for landscape, originates from French word “paysage” which means scenery. Nowadays, the word encompasses a wider and deeper meaning. While in the medieval period, “landscape” was used as a synonym for “region” and “territory” in most of the Germanic languages, beginning from the 15th century landscape became a pictorial genre ...
openaire   +3 more sources

Economic Aspects in Landscape Decision-making: a Participatory Planning Tool based on a Representative Approach [PDF]

open access: yes
In this paper, we develop a method for spatial decision support that combines economic efficiency – measured by the concept of willingness to pay – with a participatory planning tool, that allows for an active collaboration among the actors involved, in ...
Blaeij, A.T. de   +2 more
core   +1 more source

Blots on the landscape [PDF]

open access: yes, 2009
Since April 2008, when the Rating (Empty Properties) Act came into effect in England and Wales, empty commercial property has been liable for the full business rate following an initial rate-free period of three months, or six months for industrial ...
Pugalis, Lee
core  

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