Results 41 to 50 of about 3,704,485 (249)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Streamflow recession patterns can help unravel the role of climate and humans in landscape co-evolution [PDF]
, 2016 Traditionally, long-term predictions of river discharges and their extremes include constant relationships between landscape properties and model parameters.
Bogaart, Patrick W. +10 more
core +3 more sources
Environmental DNABiodiversity monitoring in difficult‐to‐access areas, such as rugged mountain ranges, is currently challenging and thus often absent. Environmental DNA (eDNA) offers new opportunities to monitor remote or strictly protected areas, as rivers integrate the
Flurin Leugger +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Applied Sciences, 2020 The research on geological landscape has received more and more attention worldwide. The National Geological Park of Qian-an mud forest, located in Qian-an Country, Songyuan City (Jilin Province, China) is a rare natural geological landscape formed by ...
XiangJian Rui +7 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A framework for landscape assessment [PDF]
, 1999 The primary aim of the New Zealand Institute of Landscape Architects (NZILA) conference on landscape assessment, held at Lincoln University on 12-14 March 1999, was to identify the key elements of an assessment framework suitable for use in implementing ...
Swaffield, S
core
EcosphereForest ecosystems have been degraded globally and restoration efforts aim to reverse loss of biodiversity and ecosystem function decline including carbon storage from the atmosphere.
Monika Goralczyk +7 more
doaj +1 more source
Modelling the role of groundwater hydro-refugia in East African hominin evolution and dispersal
Nature Communications, 2017 Water is a fundamental resource, but its role in hominin evolution is not well explored. Here, the authors use a combination of groundwater, climate and agent-based models to show that groundwater availability may be critical to past patterns of ...
M. O. Cuthbert +6 more
doaj +1 more source
Cosmogenic nuclide dating of cave sediments in the Eastern Alps and implications for erosion rates
International Journal of Speleology, 2020 Karstic caves are created by water eroding and corroding rocks that can be dissolved. Since both the spring areas of caves (normally at the valley bottom) as well as the recharge is controlled by superficial processes, the morphology of the cave bears ...
Philipp Häuselmann +3 more
doaj +1 more source