Results 61 to 70 of about 952,563 (300)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Landscape and Climate Changes in Southeastern Amazonia from Quaternary Records of Upland Lakes

Atmosphere, 2023
The upland lakes (ULs) in Carajás, southeastern Amazonia, have been extensively studied with respect to their high-resolution structural geology, geomorphology, stratigraphy, multielement and isotope geochemistry, palynology and limnology.
José Tasso Felix Guimarães, Prafulla Kumar Sahoo, Pedro Walfir Martins e Souza-Filho, Marcio Sousa da Silva, Tarcísio Magevski Rodrigues, Edilson Freitas da Silva, Luiza Santos Reis, Mariana Maha Jana Costa de Figueiredo, Karen da Silva Lopes, Aline Mamede Moraes, Alessandro Sabá Leite, Renato Oliveira da Silva Júnior, Gabriel Negreiros Salomão, Roberto Dall’Agnol   +13 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Comparing Watershed‐Based eDNA Sampling and Camera Trapping for Assessing Mammal Diversity in North‐Western Bhutan

Environmental DNA
The ability of environmental DNA (eDNA) to provide rapid assessments of mammal taxa composition at the watershed scale can make it an efficient survey method on large‐scale landscapes, complementing camera traps.
Karma Sherub, Sarah Thurnheer, Martina Lüthi, Virginie Marques, Arnaud Lyet, Tashi Dhendup, Lungten Dorji, Camille Albouy, Loïc Pellissier   +8 more
doaj   +1 more source

ENSO flavors in a tree-ring δ¹⁸O record of Tectona grandis from Indonesia [PDF]

Climate of the Past, 2015
Indonesia's climate is dominated by the equatorial monsoon system, and has been linked to El Niño-Southern Oscillation (ENSO) events that often result in extensive droughts and floods over the Indonesian archipelago.
K. Schollaen, C. Karamperidou, P. Krusic, E. Cook, G. Helle   +4 more
doaj   +1 more source

Landscape approaches for ecosystem management in Mediterranean Islands [PDF]

, 2012
This book presents a series of essays, drawing on the twm concepts of ecosystem management and landscape approaches, to elucidate and reflect on the present situation and future evolution of Mediterranean islands.
Baldacchino, Godfrey, Belkayali, Nur, Boissevain, Jeremy, Busuttil, Salvino, Camilleri, Alex, Cassar, Louis F., Chelazzi, Lorenzo, Colombini, Isabella, Conrad, Elisabeth, Cordina, Gordon, Farrugia, Nadia, Gallà, Damiano, Griffiths, Geoffrey H., Makhzoumi, Jala, Morse, Stephen, Phillips, Adrian, Priore, Riccardo, Roe, Maggie, Tazebay, Ilkden, Terkenli, Theano S., Vogiatzakis, Ioannis N., Çakci, Isil   +21 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Environmental DNA recovers fish composition turnover of the coral reefs of West Indian Ocean islands

Ecology and Evolution
Islands have been used as model systems to study ecological and evolutionary processes, and they provide an ideal set‐up for validating new biodiversity monitoring methods.
Mélissa Jaquier, Camille Albouy, Wilhelmine Bach, Conor Waldock, Virginie Marques, Eva Maire, Jean Baptiste Juhel, Marco Andrello, Alice Valentini, Stéphanie Manel, Tony Dejean, David Mouillot, Loïc Pellissier   +12 more
doaj   +1 more source

Role of triaxiality in the ground state shape of neutron rich Yb, Hf, W, Os, and Pt isotopes [PDF]

, 2009
The evolution of the ground-state shape along the triaxial landscape of several isotopes of Yb, Hf, W, Os, and Pt is analyzed using the self-consistent Hartree-Fock-Bogoliubov approximation.
Fossion R, Goodman A L, Iachello F, L M Robledo, Nazarewicz W, P Sarriguren, R Rodríguez-Guzmán, Ring P   +7 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source