Results 51 to 60 of about 5,495 (213)

Spatiotemporal changes in landscape patterns in karst mountainous regions based on the optimal landscape scale: A case study of Guiyang City in Guizhou Province, China

open access: yesEcological Indicators, 2023
The accurate analysis of landscape pattern and ecological process characteristics in rapidly urbanized areas is crucial for formulating policies related to differentiated urban development and landscape management measures.
Changyue Hu   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Landscape pattern evolution of the north of Hangzhou bay coastal area in Shanghai

open access: yes上海师范大学学报. 自然科学版, 2012
Since the 1980s in Shanghai,fast economic development,rapid urbanization,population explosion,all of these phenomena are driving radical changes in landscape pattern of coastal area.The landscape pattern evolution at the coastal regions of the north of ...
LIANG Shuai, GAO Jun
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

PM2.5 Sink-Source Dichotomy in Urban Clusters: Land Cover Efficiency Gradients and Socio-Meteorological Interactions

open access: yesAtmosphere
Urban clusters face escalating atmospheric challenges, with elevated PM2.5 concentrations representing a critical environmental constraint. This study investigates spatiotemporal evolution mechanisms of PM2.5 within China’s Taiyuan-Yuci-Xinzhou (TYX ...
Jian Yao, Yaolong Zhao
doaj   +1 more source

Analysis of the effect of landscape component classification on landscape diversity index

open access: yesEnvironmental Research Communications
Abstract The landscape diversity index (LDI) is an important level in biodiversity conservation, and its scale dependence has an important role in regional landscape planning and biological conservation. The aim of this study is to analyze in depth the effects of spatial scale changes in the classification of different landscape ...
Biao Ma   +3 more
openaire   +2 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Analysis of the Evolution of Land Use Carbon Metabolism Patterns and the Response to Urban Form Changes in Haikou, China

open access: yesLand
It is increasingly recognized that urban planning is essential in promoting low-carbon urban development, and the research on urban carbon metabolism patterns informs the theoretical support for carbon neutrality through urban structural optimization. To
Zuoyuan Zhang   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Assessing Spatial Fragmentation: An Analysis Utilizing Multi-Source Data in Xi’an, China

open access: yesISPRS International Journal of Geo-Information
The urban fringe, a critical transitional zone between urban and rural areas, exhibits the most intense land-use conflicts and the most dynamic spatial restructuring.
Wenda Wang   +8 more
doaj   +1 more source

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