Results 41 to 50 of about 235,338 (260)

Towards More Equitable Urban Greening: A Framework for Monitoring and Evaluating Co-Governance

Urban Planning
Urban greening has grown in significance in Europe and worldwide as a presumed “public good” initiative, delivering a range of benefits for human health and wellbeing.
Eleanor Chapman, Viktor Bukovszki, Martina van Lierop, Silvia Tomasi, Stephan Pauleit   +4 more
doaj   +1 more source

Associations between landscape values, self-reported knowledge, and land-use: a public participation GIS assessment

Ecosystems and People, 2022
While previous socio-ecological systems research has shown relationships between local knowledge and the assignment of landscape values, the relationships between value assignment and more nuanced forms of local knowledge remain less understood.
Sara Zaman, Silviya Korpilo, Andra-Ioana Horcea-Milcu, Christopher Raymond   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A study on Ecotect application of local climate at a residential area in Chuncheon, Korea

Journal of Environmental Engineering and Landscape Management, 2015
The local climate data were investigated at a residential area in Chuncheon from May to October in 2013.In addition, the simulations were carried out by the Autodesk Ecotect Analysis tool. Site A had the lowest temperature in summer.
Qian Wu, Hyun-Kil Jo
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The Future of Traditional Landscapes: Discussions and Visions

Land, 2019
At the 2018 meeting of the Permanent European Conference for the Study of the Rural Landscape (PECSRL), that took place in Clermont-Ferrand and Mende in France, the Institute for Research on European Agricultural Landscapes e.V.
Hans Renes, Csaba Centeri, Alexandra Kruse, Zdeněk Kučera   +3 more
doaj   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Sea level rise escape planning for Florida’s coastal ecosystems

Discover Conservation
Rapid transformations in coastal ecosystems brought on by climate change and sea-level rise require adaptive conservation strategies to maintain ecological connectivity into the future.
Eve Bohnett, Michael O’Brien, Reed Noss, Laura Doyle, Paul J. Young, Asena Goren, Thomas S. Hoctor   +6 more
doaj   +1 more source