Results 61 to 70 of about 235,338 (260)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Female Phalangium opilio use fellatio to compensate sexual avoidance

Scientific Reports
Sexual conflict arises from differences in reproductive interests between the sexes. We allowed the female harvestman Phalangium opilio to sequentially mate with two different males to examine female sexual receptivity in this species.
Pavol Prokop, Juraj Litavský, Zuzana Provazník   +2 more
doaj   +1 more source

Soil carbon, nitrogen and phosphorus distribution in grassland systems, important for landscape and environment

Journal of Environmental Engineering and Landscape Management, 2013
The accumulation of organic carbon (SOC), nitrogen (N) and phosphorus (P) in the soils of protected areas and agrarian lands in Central Lithuania was assessed.
Alvyra Šlepetienė, Inga Liaudanskienė, Jonas Šlepetys, Vaclovas Stukonis, Ieva Jokubauskaitė   +4 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Co‐occurring orchid species associated with different low‐abundance mycorrhizal fungi from the soil in a high‐diversity conservation area in Denmark

Ecology and Evolution
Plant–fungal interactions are ubiquitous across ecosystems and contribute significantly to plant ecology and evolution. All orchids form obligate symbiotic relationships with specific fungi for germination and early growth, and the distribution of ...
Ida Hartvig, Chatchai Kosawang, Hanne Rasmussen, Erik Dahl Kjær, Lene Rostgaard Nielsen   +4 more
doaj   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

Landscape Character and Management Zones in Polder Landscapes: A Case Study of the Dongting Lake Area

Land
Polder landscapes, as a representative of lowland agriculture landscapes, possess diverse natural and cultural values. However, polder landscapes are facing multiple challenges arising from economic and climate changes, including increasing flood threats
Jianan Deng, Qing Lin
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Participatory Mapping in a Developing Country Context: Lessons from South Africa

Land, 2019
Digital participatory mapping improves accessibility to spatial information and the way in which knowledge is co-constructed and landscapes co-managed with impoverished communities.
Dylan Weyer, Joana Carlos Bezerra, Alta De Vos   +2 more
doaj   +1 more source