Results 61 to 70 of about 437,940 (300)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Spatially explicit farming system modelling for an efficient agri-environmental policy design [PDF]

open access: yes
A mathematical programming model is developed and associated to a spatial pattern index (Ripley L function) to analyse the optimal reserve design and implementation for the Little Bustard conservation in Plaine de Niort.
Bamiere, Laure   +3 more
core   +4 more sources

Landscape change patterns at three stages of the construction and operation of the TGP

open access: yesScientific Reports, 2021
Analyses of landscape change patterns that are based on elevation and slope can not only provide reasonable interpretations of landscape patterns but can also help to reveal evolutionary laws.
Ruikang Li   +3 more
doaj   +1 more source

Effects of Mosaic Natural Conditions on the Tourism Management of a Lowland Water Reservoir, Lake Tisza, Hungary

open access: yesLand, 2023
The increasing number of visitors and conflicts resulting from shared use in valorising sensitive wetlands make effective visitor and site management measures essential.
Borbála Benkhard   +9 more
doaj   +1 more source

Um paradigma alternativo para o ordenamento do território e o turismo em paisagens costeiras: as métricas espaciais como indicadores para ordenamento e o turismo em paisagens costeiras [PDF]

open access: yes, 2018
Coastal urbanization dynamics in the Algarve are intimately related with tourism, which dominates the regional economy. We present part of the results of a research project in the coastal landscapes of Algarve, focusing on land use and land change ...
Botequilha-Leitão, André   +1 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Influence of landscape pattern changes on water conservation capacity: A case study in an arid/semiarid region of China

open access: yesEcological Indicators
With the accelerating changes of land use/cover caused by natural and human factors, landscape pattern has undergone significant changes. Given the scarcity of water resources and the degradation of ecological functions in arid and semi-arid regions of ...
Changxue Wu   +4 more
doaj   +1 more source

Complementary network-based approaches for exploring genetic structure and functional connectivity in two vulnerable, endemic ground squirrels [PDF]

open access: yes, 2017
The persistence of small populations is influenced by genetic structure and functional connectivity. We used two network-based approaches to understand the persistence of the northern Idaho ground squirrel (Urocitellus brunneus) and the southern Idaho ...
Adi Barocas   +15 more
core   +3 more sources

Integration of InVEST-habitat quality model with landscape pattern indexes to assess mountain plant biodiversity change: A case study of Bailongjiang watershed in Gansu Province [PDF]

open access: yesJournal of Geographical Sciences, 2019
Mountains in western China, hosted rich biodiversity and millions of people and inhabitant with vital ecosystem services, had experienced the most serious biodiversity loss with fragile ecological problems. Even though increasing attentions had been paid to this issue, we still lacked efficient methods to assess the change of plant biodiversity at ...
Jie Gong   +4 more
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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