Results 71 to 80 of about 74,383 (294)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Landscape and Urban Planning, 2016 Abstract Landscape fragmentation has been identified as a major threat to biodiversity worldwide. Several landscape metrics have been developed to quantify the extent of fragmentation, of which the Effective Mesh Size Index (meff) is one of the most widely used. However, its relevance for analysing the effect of fragmentation on biodiversity patterns
Schmiedel, Inga, Culmsee, Heike
openaire +2 more sources
, 2008 As one of three important ecosystems in the world ,wetland has complex , various and specific functions. With the change of its component ,the wetland ecosystem function is changing .
Liang,Shou-Zhen, Shou-zhen Liang
core +1 more source
Landscape vulnerability index.
, 2023 Conducting ecological risk assessment of fragile ecological landscapes is a prerequisite for building an ecological security pattern and a necessary consideration for sustainable development.
Jie Zhang (64655) +3 more
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Study on wetland landscape pattern evolution in the Dongping Lake
, 2022 Wetland structure evolution is a basis of healthy ecosystem and one of the important indicators for restoration and protection of wetlands. In this paper, based on the Landsat remote sensing images from 1980 to 2020, the wetland structure was extracted ...
Ke Zhou
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Environmental Research CommunicationsThe source region of the Yellow River is an important ecological barrier of the Qinghai-Tibet Plateau in China. In recent decades, the ecological environment in the source region of the Yellow River has been deteriorating continuously, which not only ...
Si Jianhua +9 more
doaj +1 more source
, 2022 The ecological restoration of territorial space emphasizes the synergy between ecology and social development. On this basis, we used landscape index analysis methods to explore the spatiotemporal evolution of landscape patterns in urban areas on a ...
Fayong Li, Wenwen Xu, Xuewei Hu
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source