Results 81 to 90 of about 437,940 (300)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Effects of the Sustainable Forestry Initiative on Landscape Pattern and Processes [PDF]

open access: yes, 2006
We used simulation modeling to study the changes in landscape pattern and function resulting from the application of the Sustainable Forestry Initiative (SFI) program in East Texas, USA.
Azevedo, João   +4 more
core  

Relating spatial pattern of forest cover to accessibility [PDF]

open access: yes, 2007
Urban planning for optimal provision of recreational forests is not only concerned with how much space is needed, but equally with how this could be arranged in the landscape in order to make these forests accessible to many potential visitors.
De Clercq, Eva   +2 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Spatiotemporal Change and Landscape Pattern Variation of Eco-Environmental Quality in Jing-Jin-Ji Urban Agglomeration From 2001 to 2015

open access: yesIEEE Access, 2020
Identifying the changes and relationships between regional eco-environment quality and landscape pattern in an urban agglomeration have a great significance in realizing sustainable development goal.
Jianwan Ji   +4 more
doaj   +1 more source

Fast approximation of visibility dominance using topographic features as targets and the associated uncertainty [PDF]

open access: yes, 2003
An approach to reduce visibility index computation time andmeasure the associated uncertainty in terrain visibility analysesis presented. It is demonstrated that the visibility indexcomputation time in mountainous terrain can be reduced substantially ...
Rana, S
core   +1 more source

Morse Index Classification and Landscape of Kuramoto System for Hebbian-based Binary Pattern Recognition

open access: yes
This study examines the Kuramoto model with a Hebbian learning rule and second-order Fourier coupling for binary pattern recognition. The system stores memorized binary patterns as stable critical points, enabling it to identify the closest match to a defective input.
Zhao, Xiaoxue, Zhou, Xiang
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A study on the evolution of landscape pattern and driving factors from 1990 to 2020 in the source region of the Yellow River in China

open access: yesEnvironmental Research Communications
The source region of the Yellow River is an important ecological barrier of the Qinghai-Tibet Plateau in China. In recent decades, the ecological environment in the source region of the Yellow River has been deteriorating continuously, which not only ...
Si Jianhua   +9 more
doaj   +1 more source

Frustration in Biomolecules [PDF]

open access: yes, 2013
Biomolecules are the prime information processing elements of living matter. Most of these inanimate systems are polymers that compute their structures and dynamics using as input seemingly random character strings of their sequence, following which they
Ferreiro, Diego U.   +2 more
core   +2 more sources

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