Results 121 to 130 of about 16,161,426 (301)

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Historical Landscape Structures and Their Importance for Landscape Character

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
This paper deals with studying and mapping of historical landscape structures, specifically with the so-called „unintended landscape composition“, i. e. with such a landscape structures that did not arise with the compositional intent, but by means of economic exploitation.
Petr Kučera   +3 more
openaire   +2 more sources

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

Analysis of adaptive walks on NK fitness landscapes with different interaction schemes

open access: yes, 2015
Fitness landscapes are genotype to fitness mappings commonly used in evolutionary biology and computer science which are closely related to spin glass models.
Krug, Joachim, Nowak, Stefan
core   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall   +9 more
wiley   +1 more source

Density, structure and management of landscape elements on Danish organic farms [PDF]

open access: yes, 2005
Density and management of landscape elements on organic farms were investigated for 345 organic farms in Denmark in 2001, representing approximately 10% of the total number of organic farms. The density of hedgerows, area habitats and ponds was estimated
Frederiksen, Pia, Langer, Vibeke
core  

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

From Fields to Microclimate: Assessing the Influence of Agricultural Landscape Structure on Vegetation Cover and Local Climate in Central Europe

open access: yesRemote Sensing
Agricultural intensification through simplification and specialization has homogenized diverse landscapes, reducing their heterogeneity and complexity.
Jan Kuntzman, Jakub Brom
doaj   +1 more source

The Physician‐Scientist Pipeline for Pediatric Rheumatology – Current Landscape and Future Perspectives.

open access: yesArthritis Care &Research, Accepted Article.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu   +2 more
wiley   +1 more source

Modification of Land Cover in a Traditional Agroforestry System in Spain: Processes of Tree Expansion and Regression

open access: yesEcology and Society, 2008
Europe's traditional cultural landscapes have undergone significant land-use and land-cover changes in the past 50 yr. Land-cover inventories facilitate the quantification of the conversion from one land-cover unit to another. However, they often fail to
Tobias Plieninger, Michael Schaar
doaj   +1 more source

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