Results 111 to 120 of about 327,471 (314)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

How do Changes in Land Use Patterns Affect Species Diversity? an Approach for Optimizing Landscape Configuration [PDF]

open access: yes
Heterogeneity of agricultural landscapes is supposed to be of significant importance for species diversity in agroecosystems (Weibull et al. 2003). Thus it is necessary to account for structural aspects of landscapes in land management decision processes.
Ralf Seppelt   +2 more
core  

Land-Use Change Related to Topography and Societal Drivers in High-Mountains – A Case Study in the Upper Watershed of the Tergi (Kazbegi Region), Greater Caucasus

open access: yesEuropean Countryside, 2019
High mountain ecosystems, with strong topographic and climatic gradients, are fragile and particularly sensitive to changes in land use. The abandonment of historic cultural landscapes has often led to changes in the pattern of land cover and thus, to a ...
Theissen Tim   +2 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Applying landscape ecological concepts and metrics in sustainable landscape planning

open access: yes, 2002
It is increasingly recognized that more sustainable approaches are needed for planning and managing landscapes worldwide. New tools are needed to effectively apply sustainable principles to planning and management. The spatial dimension of sustainability
Botequilha Leitão, André   +1 more
core   +1 more source

Modeling postbreakup landscape development and denudational history across the southeast African (Drakensberg Escarpment) margin [PDF]

open access: yes, 2002
We employ a numerical surface processes model to study the controls on postbreakup landscape development and denudational history of the southeast African margin.
Alastair Fleming   +9 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Landscape genetics of highly disturbed arable systems : insights gained from investigating a small mammal species

open access: yes, 2015
A large proportion of the earth’s surface is dedicated to food production, and agriculture is widely acknowledged to influence local biodiversity via habitat loss and degradation.
Wilson, Amanda
core  

The Big Asian Book of Landscape Architecture

open access: yes, 2021
Edited by Jillian Walliss from the University of Melbourne and Heike Rahmann from RMIT University, The Big Asian Book of Landscape Architecture offers fresh perspectives in the field of landscape architecture, hitherto dominated by North American and ...
Lu, X
core   +1 more source

Structural Features of Cultural Landscape in the Karst Area (Landscape in Transition)

open access: yesActa Carsologica, 2016
Na območju krasa se je v dolgi zgodovinski kontinuiteti razvil svojevrsten krajinski tip, kar je pripisati raznovrstnim podnebnim, geomorfološkim, topografskim kot tudi družbeno-gospodarskim razmeram. To zvrst označuje velika tipološka raznolikost, ki sloni na avtentičnih značilnostih naravnega in kulturnega izvora, nastala pa je kot nasledek ...
Perica, Dražen, Aničić, Branka
openaire   +4 more sources

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