Results 51 to 60 of about 2,063,143 (381)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Tweets in the Peak: Twitter Analysis - the impact of Covid-19 on cultural landscapes

Internet Archaeology, 2022
The Covid-19 pandemic had an unprecedented impact on society, with restrictions on socialising and movement during the three lockdown periods between March 2020 and March 2021 (Baker et al. 2021; Institute for Government Analysis 2021). Easily accessible
Martina Tenzer
doaj   +1 more source

Adaptive walks on time-dependent fitness landscapes

, 1999
The idea of adaptive walks on fitness landscapes as a means of studying evolutionary processes on large time scales is extended to fitness landscapes that are slowly changing over time.
A. Babajide, A. Berry, B. Charlesworth, B. Levitan, B. Levitan, C. Adami, C. Reidys, C. V. Forst, C. V. Forst, C. W. Reynolds, D. Stauffer, E. van Nimwegen, H. I. Freedman, J. H. Gillespie, J. P. Crutchfield, J. S. Gale, J. W. Thatcher, K. Ishii, M. A. Huynen, M. Eigen, M. Kimura, M. Kreitman, M. Kreitman, M. Kreitman, R. Lande, S. A. Kauffman, S. A. Kauffman, S. A. Kauffman, S. Benner, T. Bäck, W. D. Hillis, W. J. Ewens   +31 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Exploring the Potential and Contribution of UNESCO Biosphere Reserves for Landscape Governance and Management in Africa

Land, 2020
United Nations Educational Scientific and Cultural Organization (UNESCO) Biosphere Reserves strive for a harmonious interaction between humans and nature.
Bettina Hedden-Dunkhorst, Florian Schmitt   +1 more
doaj   +1 more source

Land‐sharing/‐sparing connectivity landscapes for ecosystem services and biodiversity conservation

People and Nature, 2019
1. The land-sharing versus land-sparing debate recently stagnated, lacking an integrating perspective in agricultural landscapes as well as consideration of ecosystem services. Here, we argue that land-sharing (i.e. wildlife-friendly farming systems) and
I. Grass, Jacqueline Loos, Svenja Baensch, P. Batáry, Felipe Librán-Embid, A. Ficiciyan, Felix Klaus, Maraja Riechers, Julia Rosa, Julia Tiede, Kristy Udy, C. Westphal, A. Wurz, T. Tscharntke   +13 more
semanticscholar   +1 more source

Quantum Control Landscapes

, 2007
Numerous lines of experimental, numerical and analytical evidence indicate that it is surprisingly easy to locate optimal controls steering quantum dynamical systems to desired objectives.
Agrachev AA, Beltrani V, Herschel Rabitz, Jurdjevic V, Raj Chakrabarti, von Neumann J   +5 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Exact Results for Amplitude Spectra of Fitness Landscapes

, 2013
Starting from fitness correlation functions, we calculate exact expressions for the amplitude spectra of fitness landscapes as defined by P.F. Stadler [J. Math. Chem.
Krug, Joachim, Neidhart, Johannes, Szendro, Ivan G.   +2 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source