Results 81 to 90 of about 1,983,901 (377)
Characterizing Potentials by a Generalized Boltzmann Factor [PDF]
Based on the concept of a nonequilibrium steady state, we present a novel method to experimentally determine energy landscapes acting on colloidal systems.
C. Bechinger +4 more
core +1 more source
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Robotic 3DCP fabrication of custom-fit slabs for irregular pontoons
This paper presents a case study on the use of 3D concrete printing (3DCP) to qualify rocky pontoons with spaces for recreational use—namely sitting areas, circulation trails and fishing spots—and biodiversity protection—providing habitat and refuge for ...
João Ribeiro +5 more
doaj +1 more source
Properties of selected mutations and genotypic landscapes under Fisher's Geometric Model
The fitness landscape - the mapping between genotypes and fitness - determines properties of the process of adaptation. Several small genetic fitness landscapes have recently been built by selecting a handful of beneficial mutations and measuring fitness
Achaz, Guillaume +3 more
core +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
The Grand-Est region counted around 65 monasteries of the order of Cîteaux, founded between 1115 (Clairvaux) and before 1274 (Consolation). The presence of these abbeys and their barns, rural establishments attached to them, was a real marker of the ...
Benoit Rouzeau, Agnès Charignon
doaj +1 more source
Landscapes of Production-Landscapes for Consumption [PDF]
This paper is the second part of an exploration into the history and meaning of landscapes, based on a case study of the “must-see” scenic spots or Eight Views (bajing ??) of Linfen County in the south of China's Shanxi province. While the first part focused on the value of these iconic landscapes as sources of identity, here I will show how their ...
openaire +2 more sources
Perception of native grasslands in south-eastern Australia: some implications for landscape aesthetics and other landscape values [PDF]
Grasslands are considered to be Australia’s most threatened ecosystems, yet relatively little is known about human preferences and attitudes which contribute to continued degradation of these landscapes.
Cary, John, Williams, Kathryn
core
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Communities of practice in landscapes of practice
The original formulation of communities of practice primarily focused on describing how learning, meaning, and identity within a community can translate into a sustained practice. Wenger-Trayner et al.
Igor Pyrko, Viktor Dörfler, C. Eden
semanticscholar +1 more source

