Results 111 to 120 of about 133,759 (309)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Inhabiting - landscapes and natures [PDF]
, 2002 About the book: The Handbook of Cultural Geography presents a state of the art assessment of the key questions informing cultural geography. Emphasizing the intellectual diversity of the discipline, the Handbook presents a comprehensive statement of the ...
Hinchliffe, Steve
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Effect of Seaweed Extract and Fertilization NPK On the Growth of Bougainvillea Dwarf Pink Plant
Maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗThe study aimed to reveal the effect of adding seaweed extract and macronutrients NPK on the growth characteristics of Bougainvillea Dwarf Pink.
Zeyad M. Abdulrazzaq +1 more
doaj +2 more sources
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Integrated Nutrient Management’s Impact on Dahlia Cultivation (Dahlia variabilis L.) cv. Zail Singh
BioResourcesThe experiment was conducted during the winter season of 2022–2023 at the Horticultural Research Centre, SVPUA&T, Meerut, to evaluate the impact of Integrated Nutrient Management (INM) on Dahlia variabilis L. cv.
Krishna Kaushik +9 more
doaj