Results 111 to 120 of about 29,666 (295)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Plant Viability in an Urbanized Environment
Лесной журналThe aim of the study has been to analyze the vitality of woody plants in an urbanized environment to solve the problems of landscaping a large city (using the example of Khabarovsk).
Galina Yu. Morozova
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Integrated Nutrient Management’s Impact on Dahlia Cultivation (Dahlia variabilis L.) cv. Zail Singh
BioResourcesThe experiment was conducted during the winter season of 2022–2023 at the Horticultural Research Centre, SVPUA&T, Meerut, to evaluate the impact of Integrated Nutrient Management (INM) on Dahlia variabilis L. cv.
Krishna Kaushik +9 more
doaj
Landscape as mediator, landscape as commons: an introduction
, 2015 Il contributo propone una trattazione dei due temi chiavi che si intersecano nel volume, andando a costituire non solo una introduzione ai saggi ivi contenuti, ma una più ampia trattazione delle questioni attorno a cui questi si muovono: le potenzialità del concetto di paesaggio considerato come intermediario/mediatore e come bene comune/commons.
CASTIGLIONI B +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source