Results 91 to 100 of about 29,666 (295)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Effect of spraying with 5-aminolevulinic acid and nano-zinc oxide on enhancing floral traits of seedlings dwarf pink Bougainvillea ‘Jewel Pink’

open access: yesActa Agriculturae Slovenica
The research sought to examine the impact of foliar application of 5-Aminolevulinic Acid and Nano-Zinc Oxide on mitigating flower drop, prolonging blooming duration of dwarf pink Bougainvillea ‘Jewel Pink’, in addition to promoting growth ...
Bushra Alawi HUSSAIN KHALAF   +1 more
doaj   +1 more source

Morphophenological characterization of ornamental ginger and selection for landscape use

open access: yesOrnamental Horticulture, 2018
Many species of Zingiber have great ornamental potential, due to durability and exotic appearance of the inflorescences. Despite its large phenotypic variability, they are scarcely exploited or not yet exploited regarding the ornamental potential.
Carlos Eduardo Ferreira de Castro   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Landscaping

open access: yes, 2008
MC022A new real estate development in an old neighborhood uses the adjacent stream for its common ...
Craig Denton
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The changes of heavy metals and some necessary elements in leaf, fruit and soil on apple cultivar golden delicious by applying urban treated wastewater

open access: yesBMC Plant Biology
Background Reuse of treated wastewater is a long-standing yet increasingly vital approach to alleviating water scarcity challenges in agricultural development.
Mehdi Nasirpour   +4 more
doaj   +1 more source

Cocopeat-amended leaf mould compost yields quality potted dahlia specimens under shade net intercepting one-third sunlight

open access: yesAdvances in Horticultural Science
Growers in tropical and subtropical climates with higher afternoon solar intensities face challenges while cultivating potted dahlias. Dahlias that are cultivated in pots with limited capacity lose a great deal of their quality when it gets hot outside.
Simrat Singh, Aradhna
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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