Greener Golf: Promoting a More Sustainable Game [PDF]
, 2020 : At a confluence of accelerating climate change, unprecedented technological advancement, and increasing corporate and government transparency, global systems are reaching a level of complexity never seen before.
core
The pan-cancer landscape of crosstalk between epithelial-mesenchymal transition and immune evasion relevant to prognosis and immunotherapy response [PDF]
, 2021 Guangyu Wang +9 more
openalex +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
International Documents on Landscape Restoration
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015 In the theory and practice of cultural monuments protection, including garden art monuments and landscape protection, it has been often referred to international conventions and other international documents relating to this protection.
Olga Pouperová +2 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Algorithm for the Development of Public Spaces in Large Cities in the Context of Urbanization
Регионология, 2020 Introduction. When selecting urbanized locations for parks and squares as centers of improvement and comfort of the urban environment, it is necessary to involve not only public authorities, but also activists.
Sergey G. Tyaglov +3 more
doaj +1 more source
The quality of district plans and their implementation: Towards environmental quality [PDF]
, 2002 Since inception of the Resource Management Act 1991 (RMA) the issue of sustainable management has dominated planning practice in New Zealand. Over the past decade, councils have wrestled with converting the concept of sustainable management into policy
Backhurst, Michael +7 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The implications of alternative developer decision-making strategies on land-use and land-cover in an agent-based land market model [PDF]
, 2012 Land developers play a key role in land-use and land cover change, as\ud they directly make land development decisions and bridge the land and housing\ud markets.
Brown, D.G. +6 more
core +1 more source
Sustainability, 2019 Electronic waste (e-waste) represents a severe global environmental issue due to the fast upgrading and updating of electronic products and the high environmental risk.
Fu Chen +5 more
semanticscholar +1 more source