Results 51 to 60 of about 1,841,934 (257)

Macroscopic modeling of lane-changing for two-lane traffic flow

, 2009
We propose a macroscopic model of lane-changing that is consistent with car-following behavior on a two-lane highway. Using linear stability theory, we find that lane-changing affects the stable region and the propagation speeds of the first-order and ...
Tang, TQ, Zhang, P, Huang, HJ, Wong, SC
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Modeling collision risk for unsafe lane-changing behavior: A lane-changing risk index approach

Alexandria Engineering Journal
The lane-changing maneuvers are challenging and contributes to traffic accidents and crashes. They are complicated task that often lead to an increased risk of vehicle collisions and deteriorates traffic flow. This paper proposes a vehicle collision risk
Muhammad Sameer Sheikh, Yinqiao Peng
doaj   +1 more source

Research on Decision-Making Behavior of Discretionary Lane-Changing Based on Cumulative Prospect Theory

Journal of Advanced Transportation, 2020
In this paper, the decision-making model of discretionary lane-changing is established using cumulative prospect theory (CPT). Through analyzing the vehicles’ dynamic running states, safety spacing calculating approaches for discretionary lane-changing ...
Xueqin Long, Liancai Zhang, Shanshan Liu, Jianjun Wang   +3 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Exploring Sustainable Lane-Change Behaviours – Integrated Approach to Modelling Mixed Traffic with Intelligent-Connected Vehicles

Promet (Zagreb)
This paper proposes two sustainable lane-changing (LC) decision-making models for application in intelligent-connected (I-C) and mixed-traffic environments.
Xushan FANG, Peikun LIAN, Wei HUANG, Chao WANG, Said M. EASA, Shuang LIN, Ning CHEN   +6 more
doaj   +1 more source

A Novel Dynamic Lane-Changing Trajectory Planning Model for Automated Vehicles Based on Reinforcement Learning

Journal of Advanced Transportation, 2022
Lane changing behavior has a significant impact on traffic efficiency and may lead to traffic delays or even accidents. It is important to plan a safe and efficient lane-changing trajectory that coordinates with the surrounding environment.
Cenxin Yu, Anning Ni, Jing Luo, Jinghui Wang, Chunqin Zhang, Qinqin Chen, Yifeng Tu   +6 more
doaj   +1 more source

Vehicles Lane-changing Behavior Detection

CoRR, 2018
The lane-level localization accuracy is very important for autonomous vehicles. The Global Navigation Satellite System (GNSS), e.g. GPS, is a generic localization method for vehicles, but is vulnerable to the multi-path interference in the urban environment.
Iljoo Baek, Mengwen He
openaire   +2 more sources

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source