Results 41 to 50 of about 773 (166)

Research on Decision-Making Behavior of Discretionary Lane-Changing Based on Cumulative Prospect Theory

Journal of Advanced Transportation, 2020
In this paper, the decision-making model of discretionary lane-changing is established using cumulative prospect theory (CPT). Through analyzing the vehicles’ dynamic running states, safety spacing calculating approaches for discretionary lane-changing ...
Xueqin Long, Liancai Zhang, Shanshan Liu, Jianjun Wang   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Modeling collision risk for unsafe lane-changing behavior: A lane-changing risk index approach

Alexandria Engineering Journal
The lane-changing maneuvers are challenging and contributes to traffic accidents and crashes. They are complicated task that often lead to an increased risk of vehicle collisions and deteriorates traffic flow. This paper proposes a vehicle collision risk
Muhammad Sameer Sheikh, Yinqiao Peng
doaj   +1 more source

A Novel Dynamic Lane-Changing Trajectory Planning Model for Automated Vehicles Based on Reinforcement Learning

Journal of Advanced Transportation, 2022
Lane changing behavior has a significant impact on traffic efficiency and may lead to traffic delays or even accidents. It is important to plan a safe and efficient lane-changing trajectory that coordinates with the surrounding environment.
Cenxin Yu, Anning Ni, Jing Luo, Jinghui Wang, Chunqin Zhang, Qinqin Chen, Yifeng Tu   +6 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Deep Q‐network based multi‐layer safety lane changing strategy for vehicle platoon

IET Intelligent Transport Systems
The vehicle platoon lane changing is significant for alleviating road congestion and diminishing transportation energy consumption. However, the lane changing strategy for a group of vehicles is still a great challenge in this field.
Jinqi Zhang, Maode Yan, Lei Zuo
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Modeling of Lane Changing Behavior of Connected Driving Based on Vehicle Interaction Potential

Applied Sciences
Aiming at the interactive behavior of vehicles changing lanes in the intelligent network traffic environment, the relative position of vehicle, speed, acceleration, and steering angle are introduced to correct the molecular interaction potential, and the
Juan Li, Dayi Qu, Yicheng Chen, Yuxiang Yang, Shanning Cui   +4 more
doaj   +1 more source

End-to-End Automated Lane-Change Maneuvering Considering Driving Style Using a Deep Deterministic Policy Gradient Algorithm

Sensors, 2020
Changing lanes while driving requires coordinating the lateral and longitudinal controls of a vehicle, considering its running state and the surrounding environment.
Hongyu Hu, Ziyang Lu, Qi Wang, Chengyuan Zheng   +3 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source