Results 31 to 40 of about 773 (166)

Research on Mandatory Lane-Changing Behavior in Highway Weaving Sections

open access: yesJournal of Advanced Transportation, 2020
As the accident-prone sections and bottlenecks, highway weaving sections will become more complicated when it comes to the mixed-traffic environments with connected and automated vehicles (CAVs) and human-driven vehicles (HVs).
Wei Hao   +5 more
doaj   +1 more source

Influencing Factors of the Length of Lane-Changing Buffer Zone for Autonomous Driving Dedicated Lanes

open access: yesApplied Sciences, 2022
With the development of intelligent transportation, dedicated highway lanes for autonomous vehicles (AVs), necessary for ensuring their right of way, have emerged as critical issues in intelligent transportation research, which makes it necessary to set ...
Fujin Hou   +5 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Planning flexible and smooth paths for lane‐changing manoeuvres of autonomous vehicles

open access: yesIET Intelligent Transport Systems, 2021
Lane‐changing manoeuvres are essential for daily driving tasks. Safety and comfort are the primary issues to be considered during the lane‐changing manoeuvres of autonomous vehicles. However, because the traffic environment is complicated and changeable,
Bo Zhang   +4 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

A state dependent mandatory lane-changing model for urban arterials with hidden markov model method

open access: yesInternational Journal of Transportation Science and Technology, 2019
The inherent intention and decision process of lane changes are complex. Though the external environment and traffic conditions are changing along the traveling direction, the drivers’ characteristics and preferences may lead to persistence of preferable
Xiduo Wang, Yunlong Zhang, Jian Jiao
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Exploring Sustainable Lane-Change Behaviours – Integrated Approach to Modelling Mixed Traffic with Intelligent-Connected Vehicles

open access: yesPromet (Zagreb)
This paper proposes two sustainable lane-changing (LC) decision-making models for application in intelligent-connected (I-C) and mixed-traffic environments.
Xushan FANG   +6 more
doaj   +1 more source

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