Results 161 to 170 of about 252,737 (261)

Lane-Changing Model in SUMO

open access: yes, 2014
SUMO is an open source microscopic traffic simulation. A major component of modelling microscopic vehicle behavior is the lane-changing behavior on multi-lane roads. We describe a new model which uses a 4-layered hierarchy of motivations to determine the vehicle behavior during every simulation step and motivate in which ways it improves the current ...
openaire   +1 more source

Where Do We Fit? Reflections on Research Interview Practice, Project Design, and Interpretation**

open access: yesBerichte zur Wissenschaftsgeschichte, EarlyView.
What is special about historical research interviews in the history of science, technology, and medicine, and how do they compare to the tools of oral historians and social scientists? This essay reflects on three interview projects I have undertaken, each taking a distinct shape.
Dmitriy Myelnikov
wiley   +1 more source

Hydrogel Embedding of Mesenchymal Stem Cells Supports Extracellular Vesicle Production

open access: yesBiotechnology and Bioengineering, EarlyView.
This study investigates the effects of 3D culture conditions on extracellular vesicle (EV) production by mesenchymal stem cells (MSCs) in a gelatin‐based hydrogel matrix (GelMA). The EVs from both conditions were found to have similar morphological, molecular, and functional properties, but 3D cultures produced more total EVs per volume.
Rachel K. Moen   +5 more
wiley   +1 more source

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji   +5 more
wiley   +1 more source

Correction: DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma. [PDF]

open access: yesPLoS Genet
Ma RK   +13 more
europepmc   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

A review of the historic and present ecological role of aquatic and shoreline wood, from forest to deep sea

open access: yesBiological Reviews, EarlyView.
ABSTRACT The ecology of forests, their losses, and terrestrial wood decomposition dynamics have been intensively studied and reviewed. In the aquatic realm, reviews have concentrated on large wood (LW) in rivers and the transition from freshwater to marine environments in the Pacific Northwest of North America. However, a comprehensive global synthesis
Jon Dickson   +9 more
wiley   +1 more source

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