Results 211 to 220 of about 270,632 (283)

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

A Portable Colorimetric Device for Rapid Bacterial Detection with Cleavable Functional Nucleic Acid Probes for A Common Bacterial Endoribonuclease

open access: yesAngewandte Chemie, EarlyView.
A simple, rapid, and portable gold‐coated filter tip‐based assay (GFTA) is developed for bacterial detection. The GFTA leverages cleavable functional nucleic acid probes as molecular recognition elements to target RNase H2, a highly conserved bacterial endoribonuclease, enabling sensitive and specific colorimetric detection of bacterial pathogens ...
Jiuxing Li   +4 more
wiley   +2 more sources

PKM2 mediates the glycolytic response to matrix stiffness in lung fibroblasts. [PDF]

open access: yesFront Cell Dev Biol
Wang Y   +5 more
europepmc   +1 more source

Assembly of Protein‐DNA Framework Nanostructures: Structurally Defining Protein‐DNA Interfaces With Aptamer

open access: yesAngewandte Chemie, EarlyView.
Rationally designed DNA multivalent aptamers direct specific protein binding to drive self‐assembly into protein‐DNA frameworks (PDFs). Structurally defined protein‐aptamer interfaces organize proteins into triangles, linear and ladderlike chains, and periodic two‐dimensional arrays, enabling precise control over orientation, connectivity, and overall ...
Zhe Zhang   +11 more
wiley   +2 more sources

Foliar pathogen epidemic slows decomposition of invasive plant litter. [PDF]

open access: yesEcology
Lane BR   +8 more
europepmc   +1 more source

VP1-141 is a determinant of a Vero cell-adapted Coxsackievirus A10 for vaccine development. [PDF]

open access: yesPLoS Negl Trop Dis
Chen CH   +5 more
europepmc   +1 more source

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