Results 61 to 70 of about 3,259,215 (246)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Lane County food waste to energy feasibility study: final report

open access: yes, 2009
"The goal of the Lane County Food Waste to Energy Feasability Study is to determine if it is financially feasible to construct and operate a Lane County owned anaerobic digestion facility to process local food waste into energy"--Page 2."Renewable Energy

core  

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

open access: yesArthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah   +13 more
wiley   +1 more source

Lane Marks Detection Using Steerable Filters

open access: yes, 2011
[[abstract]]While applying image processing techniques to extract information from vision based traffic monitoring system, it usually requires detecting road area beforehand in order to focus on the region interested.
王俊明;鍾允中;張祥利;陳世旺   +1 more
core  

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Multi-lane line detection algorithm based on feature point instance segmentation

open access: yesJournal of Engineering and Applied Science
Accurate lane detection is a critical requirement for autonomous driving. However, it remains a challenging task in complex road scenarios, where lane markings can be occluded, worn, curved, or affected by varying illumination.
Shiping Song   +5 more
doaj   +1 more source

Lane Collection - Lane Family Portrait at "Willowhurst", circa 1910

open access: yes, 1910
Left to right: Edythe Lane, Ernest Erastus Lane, Maude Lane, and Abbie Waldron Lane on the front lawn of Willowhurst, the Lane family home in ...

core   +1 more source

Light‐Induced Field‐Tunneling Synapses in Solution‐Processed Van Der Waals Heterostructures for Scalable, Retina‐Inspired Optical Sensing

open access: yesAdvanced Functional Materials, EarlyView.
A scalable, solution‐processed WSe2/ZrO2‐x van der Waals heterostructure realizes a light‐induced field‐tunneling synapse (LIFTS) that activates exclusively under bright illumination, emulating the photopic adaptation of the human retina at the device level.
Kijeong Nam   +10 more
wiley   +1 more source

Vision-based lane detection for autonomous artificial intelligent vehicles

open access: yes, 2009
Intelligent vehicles are one of the enlightening ideas that will shape our future by providing enhanced safety and improved mobility. Apparently, among the complex and challenging tasks of future road vehicles is road lane detection or road boundaries ...
Khalifa, Othman Omran   +2 more
core  

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