Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity [PDF]
, 2005 Langerhans cells (LC) form a unique subset of dendritic cells ( DC) in the epidermis but so far their in vivo functions in skin immunity and tolerance could not be determined, in particular in relation to dermal DC ( dDC).
Clausen, B.E. +27 more
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Late-Onset Langerhans Cell Histiocytosis Presenting with Seizures and Bilateral Temporal Involvement
, 2022 Langerhans cell histiocytosis is known as a rare childhood disease. In this case, we wanted to share our patient’s experience whose first symptom was an epileptic seizure, which attracted attention at an advanced age and revealed bilateral temporal lobe ...
Özge Öcek, Hasan Kuş, Pınar Ortan
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A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of Langerhans [PDF]
, 2008 Background: The extracellular calcium-sensing receptor (CaR) is expressed in many tissues that are not associated with Ca2+ homeostasis, including the endocrine cells in pancreatic islets of Langerhans.
Persaud, Shanta J.; id_orcid +6 more
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Langerhans Cell Histiocytosis [PDF]
Advances in Anatomic Pathology, 1998 Langerhans cell histiocytosis (LCH) is a rare clonal disorder that consists of single or multiple mass lesions composed of cells with an abnormal Langerhans cell phenotype. Its etiology remains unknown, despite extensive searches for evidence of consistent cytogenetic abnormalities, gene rearrangements, or viral genomes.
K M, Herzog, R R, Tubbs
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Primary Langerhans Cell Histiocytosis of the Extrahepatic Bile Duct Occurring in an Adult Patient
Balkan Medical Journal, 2018 Background: Langerhans cell histiocytosis is characterized by an abnormal proliferation of neoplastic Langerhans cells. Langerhans cell histiocytosis commonly affects the pediatric population, whereas presentation in adults remains a rare event.
Ifeyinwa E. Obiorah +3 more
doaj +1 more source
Sphingosine 1-phosphate modulates antigen capture by murine langerhans cells via the S1P2 receptor subtype [PDF]
, 2012 Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs.
Kleuser, Burkhard (Prof. Dr. rer. nat.) +13 more
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Langerhans cell histiocytosis on the penis: a case report
BMC Urology, 2006 Background Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs.
Kuroda Isao +5 more
doaj +1 more source
Langerhans cell histiocytosis [PDF]
Blood, 2020 Abstract Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction. The pathogenic cells are defined by constitutive activation of the MAPK signaling pathway.
Carl E. Allen, Carlos Rodriguez-Galindo
openaire +2 more sources
Langerhans Cell Sarcoma of the Axillary Lymph Node: A Case Report and Review of the Literature
Turkish Journal of Hematology, 2013 Langerhans cell sarcoma is a rare, high-grade neoplasm with overtly malignant cytological features and the Langerhans phenotype. Herein, we present a rare case of Langerhans cell sarcoma in a 65-year-old female that presented with a painless enlarging ...
Aylin Orgen Çallı +4 more
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Ultrasound-assisted diagnosis of Langerhans cell hyperplasia of the sternum: A case report
Radiology Case Reports, 2021 Langerhans cell hyperplasia is a group of diseases characterized by the proliferation or dissemination of the Langerhans cell, which can come in the form of localized benign lesions, or extensive disseminated invasive neoplastic lesions.
Qian Zhang, master +4 more
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