Results 31 to 40 of about 48,040 (158)
Langerhans Cell Histiocytosis of the Skull
This is a case of a pediatric male who presented with a postauricular mass and pain. Computed tomography and magnetic resonance imaging suggested a diagnosis of Langerhans cell histiocytosis.
Adrian A. Ong MD +2 more
doaj +1 more source
Specific Protein Antigen Delivery to Human Langerhans Cells in Intact Skin
Immune modulating therapies and vaccines are in high demand, not least to the recent global spread of SARS-CoV2. To achieve efficient activation of the immune system, professional antigen presenting cells have proven to be key coordinators of such ...
Mareike Rentzsch +14 more
doaj +1 more source
Langerhans Cell Histiocytosis: An Unusual Presentation
Objective: To describe an unusual presentation of Langerhans cell histiocytosis in the craniofacial skeleton in a patient previously diagnosed with Pott’s disease. Methods: Design: Case report. Setting: Tertiary care center. Patient: One
Kathleen R. Fellizar +1 more
doaj +1 more source
Langerhans cell histiocytosis [PDF]
Abstract Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction. The pathogenic cells are defined by constitutive activation of the MAPK signaling pathway.
Carl E. Allen, Carlos Rodriguez-Galindo
openaire +2 more sources
Langerhans' Cell Histiocytosis
Adult onset Langerhans cell histiocytosis is uncommon. A 29 year old man is presented who developed classic cutaneous disease with severe systemic involvement. He responded completely to a two month course of thalidomide.
Mortazavi, Hessein +3 more
openaire +4 more sources
Rho-associated kinase regulates Langerhans cell morphology and responsiveness to tissue damage
Summary: Skin damage requires efficient immune cell responses to restore organ function. Epidermal-resident immune cells known as Langerhans cells use dendritic protrusions to surveil the skin microenvironment, which contains keratinocytes and peripheral
Eric Peterman +3 more
doaj +1 more source
Langerhans cells: an update [PDF]
SummaryLangerhans cells belong to the family of dendritic cells, professional antigen‐presenting cells, and populate the skin and epithelia of mammals. It was the extensive investigation of this particular dendritic cell subpopulation in earlier days, which contributed crucially to the current understanding of the regulation of antigen processing and ...
openaire +3 more sources
Langerhans cell histiocytosis present in a 1-day-old girl: a case report
Background Langerhans cell histiocytosis is a rare condition characterized by diverse clinical manifestations, ranging from cutaneous lesions to systemic involvement.
Yang Meng
doaj +1 more source
Background: Patients with Langerhans cell histiocytosis are at particularly high risk for central diabetes insipi-dus (CDI) due to hypothalamic-pituitary disease. Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the
Zahra Alian +2 more
doaj
Nodal Langerhans cell neoplasm: detailing the diagnostic quandaries
Langerhans cells, found in the supra-basal region of the mucous membranes in the epidermis of the skin, in lymph nodes and thymus, function as antigen-presenting cells within the histiocyte system.
Zachariah Chowdhury +3 more
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