Results 101 to 110 of about 101,166 (275)

Rho-associated kinase regulates Langerhans cell morphology and responsiveness to tissue damage

Cell Reports
Summary: Skin damage requires efficient immune cell responses to restore organ function. Epidermal-resident immune cells known as Langerhans cells use dendritic protrusions to surveil the skin microenvironment, which contains keratinocytes and peripheral
Eric Peterman, Elgene J.A. Quitevis, Camille E.A. Goo, Jeffrey P. Rasmussen   +3 more
doaj  

Modelling cell-cell collision and adhesion with the Filament Based Lamellipodium Model [PDF]

arXiv, 2018
We extend the live-cell motility Filament Based Lamellipodium Model to incorporate the forces exerted on the lamellipodium of the cells due to cell-cell collision and cadherin induced cell-cell adhesion. We take into account the nature of these forces via physical and biological constraints and modelling assumptions. We investigate the effect these new
arxiv  

Contact Urticaria and Related Conditions: Clinical Review

Contact Dermatitis, EarlyView.
ABSTRACT Contact urticaria (CoU) is an immediate contact reaction occurring within minutes to an hour after exposure to specific proteins or chemicals. CoU is categorised into non‐immunologic (NI‐CoU) and immunologic (I‐CoU) types, with I‐CoU potentially leading to anaphylaxis. Both forms of CoU can be associated with protein contact dermatitis and the
Mojca Bizjak, Olivier Aerts, David Pesqué, Melba Muñoz, Riccardo Asero, Margarida Gonçalo, Thomas Rustemeyer, Mitja Košnik, Mark Kačar, An Goossens, Jose Hernán Alfonso, Charlotte G. Mortz, Maryam Ali Al‐Nesf, Joachim W. Fluhr, Howard I. Maibach, Ana Maria Giménez‐Arnau   +15 more
wiley   +1 more source

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

Cell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye, Yanlin Li, Xiaolin Yang, Chenglin Li, Rui Yu, Guangjuan Zheng, Zuqing Su   +6 more
wiley   +1 more source

Histiocitose de células de Langerhans: doença de Letterer-Siwe - importância do diagnóstico dermatológico em dois casos Langerhans cell histiocytosis: Letterer-Siwe disease - the importance of dermatological diagnosis in two cases

Anais Brasileiros de Dermatologia, 2009
A histiocitose de células de Langerhans é proliferação clonal de células fenotipicamente semelhantes às células de Langerhans. Anteriormente denominada Letterer-Siwe, é a forma mais comum e mais grave dessa enfermidade, acometendo sobretudo crianças até ...
Leonardo Mello Ferreira, Paulo Sergio Emerich, Lucia Martins Diniz, Luciene Lage, Isabella Redighieri   +4 more
doaj   +1 more source

The cell cycle related rhythms, cells' states correlation and the cancer [PDF]

arXiv, 2015
We consider the decision making by mammalian cells, looking them as dynamic systems with rhythms. We calculate the effective dimension of the cell division model of the healthy mammalian cells consistent with the data: it is described via a four dimensional dynamic system. We assume that the cell's decision making property is strongly affected by the
arxiv  

Variation in effectiveness of the NHS Diabetes Prevention Programme in people diagnosed with non‐diabetic hyperglycaemia by age, sex, BMI, and deprivation: A matched cohort analysis of 69,801 people

Diabetic Medicine, EarlyView.
Abstract Aims The NHS Diabetes Prevention Programme (DPP) is a behaviour‐change programme aimed at adults diagnosed with non‐diabetic hyperglycaemia (NDH), who are at higher risk of developing type 2 diabetes mellitus (Diabetes). This paper explores the heterogeneity in the effectiveness of the DPP by age, sex, BMI, and practice location deprivation ...
Rathi Ravindrarajah, Matt Sutton, Peter Bower, Evangelos Kontopantelis   +3 more
wiley   +1 more source

Assessment of antigen presenting cell infiltration in lung tissues of patients with bronchiectasis

Indian Journal of Pathology and Microbiology, 2016
Background: Bronchiectasis is a chronic disease characterized by permanent dilatation of the conducting airways accompanied by sustained inflammation. Aims: To assess whether chronic inflammation of lungs in bronchiectasis is associated with alterations ...
Waseem M Hajjar, Abdulaziz H Alzeer, Amany A Fathaddin, Hadil A Al-Otair, Ammar C Al-Rikabi, Zahid Shakoor   +5 more
doaj   +1 more source

Type 1 diabetes risk factors, risk prediction and presymptomatic detection: Evidence and guidance for screening

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes is recognized as a chronic disease with a presymptomatic phase that does not require insulin therapy and a clinical phase where insulin treatment becomes necessary. The presymptomatic phase is characterized by the presence of autoantibodies targeting pancreatic islet beta cell antigens (islet autoantibodies).
Ezio Bonifacio, Anette‐Gabriele Ziegler   +1 more
wiley   +1 more source

Interactions of Human Dermal Dendritic Cells and Langerhans Cells Treated with Hyalomma Tick Saliva with Crimean-Congo Hemorrhagic Fever Virus

Viruses, 2018
Crimean-Congo hemorrhagic fever virus is one the most important and wide spread tick-borne viruses. Very little is known about the transmission from the tick and the early aspects of pathogenesis.
Sergio E. Rodriguez, Alexander J. McAuley, Aysen Gargili, Dennis A. Bente   +3 more
doaj   +1 more source