Results 91 to 100 of about 93,752 (261)

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Temporal community change in stream ecosystems varies by assemblage across US climates

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Ecosystem properties are temporally dynamic. Temporal variability has been shown to decrease with increasing levels of biological organization (i.e. from population to community and ecosystem levels).
Megan C. Malish, Stephen C. Cook, Mariana Perez Rocha, Albert Ruhí, Michael T. Bogan, Thomas M. Neeson, Daniel C. Allen   +6 more
wiley   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. [PDF]

, 1994
Dendritic cells comprise a system of highly efficient antigen-presenting cells involved in the initiation of T cell responses. Herein, we investigated the role of the CD28 pathway during alloreactive T cell proliferation induced by dendritic-Langerhans ...
Azuma, M, Banchereau, J, Caux, C, Lanier, LL, Massacrier, C, Okumura, K, Vanbervliet, B   +6 more
core  

How periodontal disease may contribute to cardiovascular disease [PDF]

, 2000
No abstract ...
Kinane, D.F., Lowe, G.D.O.
core   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber, Szabina Horváth, Balázs Zoltán Zsidó, Viktória Kormos, János Konkoly, Csaba Hetényi, Erika Pintér, Ágnes Kemény, Rolland Gyulai   +8 more
wiley   +1 more source

Effects of immunomodulatory drugs on TNF-α and IL-12 production by purified epidermal langerhans cells and peritoneal macrophages

BMC Research Notes, 2011
Background Langerhans cells constitute a special subset of immature dendritic cells localized in the epidermis that play a key role in the skin's immune response.
da Silva Jorge P, Vieira José LF, da Silva Moises B, Campelo Simone R, Salgado Claudio G   +4 more
doaj   +1 more source

An 11‐Month‐Old Infant With Unusual Diaper Dermatitis

JEADV Clinical Practice, EarlyView.
Majda Chaoui, Léo‐Paul Secco, Ifigenia Spanoudi‐Kitrimi   +2 more
wiley   +1 more source

Cutaneous Crystal‐Storing Histiocytosis With Marginal Zone Lymphoma. A Case Report With A Striking Clinical Presentation

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Cutaneous crystal‐storing histiocytosis (CSH) is an extremely rare histopathologic finding of histiocytes accumulating crystals of immunoglobulin or paraproteins, often associated with lymphoplasmacytic malignancies. It commonly presents in a wide age range of both female and male adults with a history of a lymphoproliferative disorder ...
Ashton Arlen, Brad S. Graham, Gregory A. Hosler, Marsha C. Kinney   +3 more
wiley   +1 more source

A hitchhiker's guide to myeloid cell subsets: practical implementation of a novel mononuclear phagocyte classification system [PDF]

, 2015
The classification of mononuclear phagocytes as either dendritic cells or macrophages has been mainly based on morphology, the expression of surface markers, and assumed functional specialization.
Adams, Ajami, Ajami, Bachem, Bachem, Bain, Bain, Balan, Becker, Benson, Bogunovic, Breton, Caton, Caux, Cheong, Chorro, Chou, Cisse, Contreras, Coombes, Crozat, Crozat, Crozat, Desch, Diao, Durand, Edelson, Epelman, Gao, Gatto, Gautier, Geissmann, Geurtsvankessel, Ghosh, Ginhoux, Ginhoux, Ginhoux, Gomez Perdiguero, Grajales-Reyes, Guilliams, Guilliams, Guilliams, Guilliams, Guilliams, Guilliams, Gurka, Hacker, Hashimoto, Helft, Hettinger, Hildner, Hoeffel, Hoeffel, Inaba, Jackson, Jaitin, Jakubzick, Jang, Janssen, Jha, Karsunky, Kashiwada, Kuipers, Lavin, Lee, Lewis, McKenna, Merad, Miller, Molawi, Murray, Naik, Naik, Naik, Ohl, Onai, Onai, Palucka, Persson, Plantinga, Poltorak, Poulin, Pulendran, Randolph, Reynolds, Robbins, Sallusto, Salomon, Satpathy, Saunders, Schiavoni, Schlitzer, Schlitzer, Schraml, Schulz, Scott, Serbina, Shalek, Siddiqui, Sun, Suzuki, Swirski, Tailor, Tamoutounour, Tamoutounour, Tamura, Tussiwand, van Furth, van Furth, Varol, Varol, Varol, Vu Manh, Vu Manh, Vu Manh, Waskow, Wimmers, Wu, Xu, Xue, Yamasaki, Yona, Yona, Zigmond   +123 more
core   +2 more sources