Results 91 to 100 of about 12,127,574 (275)

Effects of immunomodulatory drugs on TNF-α and IL-12 production by purified epidermal langerhans cells and peritoneal macrophages

open access: yesBMC Research Notes, 2011
Background Langerhans cells constitute a special subset of immature dendritic cells localized in the epidermis that play a key role in the skin's immune response.
da Silva Jorge P   +4 more
doaj   +1 more source

Assessing Extracellular Vesicle Proteins as Predictive Biomarkers for Developing Type 1 Diabetes

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Plasma extracellular vesicles (EVs) are considered excellent sources for biomarker discovery since they carry signatures of their cellular origin and disease processes. In this paper, we evaluate the potential of plasma EV proteomics analysis for identifying predictive biomarkers of developing type 1 diabetes (T1D), which results from ...
Panshak P. Dakup   +9 more
wiley   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

open access: yesRheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina   +3 more
wiley   +1 more source

CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

open access: yesJournal of Experimental Medicine, 2010
Recent studies have challenged the view that Langerhans cells (LCs) constitute the exclusive antigen-presenting cells of the skin and suggest that the dermal dendritic cell (DDC) network is exceedingly complex.
S. Henri   +10 more
semanticscholar   +1 more source

Chronic Ulcer on the Vulva

open access: yes
JEADV Clinical Practice, EarlyView.
Farhanaz Panjshiri   +2 more
wiley   +1 more source

Temporal community change in stream ecosystems varies by assemblage across US climates

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Ecosystem properties are temporally dynamic. Temporal variability has been shown to decrease with increasing levels of biological organization (i.e. from population to community and ecosystem levels).
Megan C. Malish   +6 more
wiley   +1 more source

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin

open access: yesImmunological Reviews, 2010
Summary:  Langerhans cells (LCs) are antigen‐presenting dendritic cells (DCs) that reside in epithelia. The best studied example is the LC of the epidermis.
N. Romani, B. Clausen, P. Stoitzner
semanticscholar   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

open access: yesActa Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry   +27 more
wiley   +1 more source

Assessment of antigen presenting cell infiltration in lung tissues of patients with bronchiectasis

open access: yesIndian Journal of Pathology and Microbiology, 2016
Background: Bronchiectasis is a chronic disease characterized by permanent dilatation of the conducting airways accompanied by sustained inflammation. Aims: To assess whether chronic inflammation of lungs in bronchiectasis is associated with alterations ...
Waseem M Hajjar   +5 more
doaj   +1 more source

External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers

open access: yesJournal of Experimental Medicine, 2009
Outermost barriers are critical for terrestrial animals to avoid desiccation and to protect their bodies from foreign insults. Mammalian skin consists of two sets of barriers: stratum corneum (SC) and tight junctions (TJs).
A. Kubo   +4 more
semanticscholar   +1 more source

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