Results 71 to 80 of about 5,656,935 (206)
Marshall Journal of Medicine, 2022 Langerhans cells are dendritic cells that form the antigenic barrier of the human body. They occur in nearly any tissue but are most prevalent in the skin, submucosa of the bronchial tree, and other mucosae.
Samantha A. Smith +4 more
doaj +1 more source
Clinical Case Reports, 2023 This is an unusual adult case of a metastatic well‐differentiated neuroendocrine tumor with incidentally discovered subtle involvement of Langerhans cell histiocytosis (LCH), a clonal proliferation of Langerhans cells.
Nancy M. Joseph, Kwun Wah Wen
doaj +1 more source
Langerhans cells: an update [PDF]
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2014 SummaryLangerhans cells belong to the family of dendritic cells, professional antigen‐presenting cells, and populate the skin and epithelia of mammals. It was the extensive investigation of this particular dendritic cell subpopulation in earlier days, which contributed crucially to the current understanding of the regulation of antigen processing and ...
openaire +3 more sources
Nail Disorders in Systemic Conditions
JEADV Clinical Practice, EarlyView.ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley +1 more source
Nail Toxicities Associated With Anticancer Therapies in Children
JEADV Clinical Practice, EarlyView.ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley +1 more source
Dendritic Cells (Langerhans Cells) in the Mouse Epidermis
, 2002 Slide 9-38: Dendritic cells (Langerhans cells) in mouse epidermishttps://digitalcommons.rockefeller.edu/diagrams/1037/thumbnail ...
Laboratory, Steinman
core +1 more source
Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib
JEADV Clinical Practice, EarlyView.ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak +2 more
wiley +1 more source
Freshly Isolated Langerhans Cells
, 1989 Freshly isolated Langerhans cells present protein antigens to activated T cells, but cultured mature cells do not From J. Exp. Med. 169: 1169-1178 (1989)https://digitalcommons.rockefeller.edu/dendritic_cell_maturation/1006/thumbnail ...
The Rockefeller University
core +1 more source
Diagnóstico precoce de histiocitose das células de Langerhans: relato de caso [PDF]
Residência PediátricaLangerhans' cells histiocytosis is a disease that belongs to the group of histiocytic disorders and is considered a rare pathology. It results from a proliferation and accumulation of cells of the phagocytic mononuclear system, including Langerhans ...
Gabriela Saraiva Mangueira +3 more
doaj +1 more source
Langerhans Cell Histiocytosis [PDF]
Cancer Control, 2014 Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
openaire +2 more sources