Results 81 to 90 of about 12,127,574 (275)
Clinical Case Reports, 2023 This is an unusual adult case of a metastatic well‐differentiated neuroendocrine tumor with incidentally discovered subtle involvement of Langerhans cell histiocytosis (LCH), a clonal proliferation of Langerhans cells.
Nancy M. Joseph, Kwun Wah Wen
doaj +1 more source
Nail Disorders in Systemic Conditions
JEADV Clinical Practice, EarlyView.ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley +1 more source
Jurnal Veteriner, 2012 Morphology, distribution and relative frequency of endocrine cells in the pancreas Bullfrog (Ranacatesbeiana) were studied using conventional and immunohistochemical methods.
I Ketut Mudite Adnyane +3 more
doaj
BMC Immunology, 2004 Background The Eph receptors are the largest receptor tyrosine kinase family. Several family members are expressed in hematopoietic cells. Previously, the expression of a member of this family, EphA2, was identified on dendritic like cells in tonsils. We
Finne Eivind +2 more
doaj +1 more source
Langerhans Cells Facilitate Epithelial DNA Damage and Squamous Cell Carcinoma
Science, 2012 The Dark Side of Langerhans Cells Several immune cell populations reside in the skin and are thought to provide a protective barrier against infections and to act as sentinels against malignant transformation.
B. Modi +16 more
semanticscholar +1 more source
Nail Toxicities Associated With Anticancer Therapies in Children
JEADV Clinical Practice, EarlyView.ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley +1 more source
Antigen Presentation by Langerhans Cells
Current Opinion in Immunology, 2012 Langerhans cells and other skin-resident dendritic cells (DC) are required for the development of cutaneous adaptive immune responses. In vivo experiments using mice with selective DC-subset deficiencies and ex vivo experiments using isolated DC suggests
B. Igyártó, D. Kaplan
semanticscholar +1 more source
Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib
JEADV Clinical Practice, EarlyView.ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak +2 more
wiley +1 more source
Langerhans cells are negative regulators of the anti-Leishmania response
Journal of Experimental Medicine, 2011 Langerhans cells suppress the immune response to low-dose Leishmania major infection in part by inducing regulatory T cells.
Kordula Kautz-Neu +6 more
semanticscholar +1 more source
Next‐Generation Paleopathology: Using Commercial AI in Bioarchaeological Diagnosis
International Journal of Osteoarchaeology, EarlyView.ABSTRACT Artificial intelligence encompasses computational systems capable of performing cognitive functions such as learning, reasoning, and problem‐solving. Within this domain, generative AI and large language models such as ChatGPT, Gemini, and Copilot have shown significant potential in clinical diagnostics.
Jessica Mongillo +4 more
wiley +1 more source