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Heterosexual transmission of HIV is the most common mode of infection in the global HIV epidemic. In the absence of an effective vaccine, there is an urgent need for additional strategies to prevent new HIV infections. Evidence from a variety of investigations, including epidemiologic studies on sexual transmission, in vivo studies in rhesus monkey ...
openaire +3 more sources
Histiocytes: Multifaceted Regulators of Health and Disease
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley +1 more source
Marked increase in B7-2/CD86 on cultured Langerhans cells From J. Exp. Med. 180: 1849-1860 (1994)https://digitalcommons.rockefeller.edu/dendritic_cell_maturation/1008/thumbnail ...
The Rockefeller University
core +1 more source
Fine‐Needle Aspirate Cytology of Feline Pulmonary Langerhans Cell Histiocytosis in Two Cats
ABSTRACT Feline pulmonary Langerhans cell histiocytosis (FPLCH) is a rare histiocytic disorder in cats, usually diagnosed post‐mortem following natural death or euthanasia for severe respiratory distress. Antemortem diagnosis has been reported only once, achieved by cytologic examination of bronchoalveolar lavage fluid combined with immunocytochemistry,
Karuna Katariwala +7 more
wiley +1 more source
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez +8 more
wiley +1 more source
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng +3 more
wiley +1 more source
ABSTRACT Erdheim–Chester disease (ECD) is a rare histiocytic disorder with heterogeneous clinical manifestations. Central nervous system (CNS) involvement is associated with poor prognosis. Although targeted therapies have improved outcomes in patients with mitogen‐activated protein kinase (MAPK) pathway alterations, optimal treatment strategies for ...
Naoki Watanabe +8 more
wiley +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Langerhans Cells-Revising Their Role in Skin Pathologies. [PDF]
Neagu M +6 more
europepmc +1 more source

