Skin-resident Langerhans cells drive neuropathic pain via chemokine-dependent neuron-immune communication. [PDF]
Pacifico P +14 more
europepmc +1 more source
Transcriptional programming of immunoregulatory responses in human Langerhans cells. [PDF]
Davies J +10 more
europepmc +1 more source
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani +4 more
wiley +1 more source
Dynamic Thymic Stromal Lymphopoietin and Its Receptor Complex Expression on Skin Langerhans Cells in Response to MC903-induced Skin Inflammation. [PDF]
González-Rodríguez MI +7 more
europepmc +1 more source
Zebrafish cutaneous injury models reveal that Langerhans cells engulf axonal debris in adult epidermis. [PDF]
Peterman E +7 more
europepmc +1 more source
HAR may improve T2DM by enhancing antioxidant defences through Nrf2 activation while suppressing inflammation and RAS activity, supporting its capability to treat diabetes. ABSTRACT Introduction Type 2 diabetes mellitus (T2DM) is strongly associated with oxidative stress and inflammation.
Farima Malekinia +5 more
wiley +1 more source
B-type natriuretic peptide attenuates TLR-induced cytokine and chemokine secretion in monocyte-derived Langerhans cells. [PDF]
Horváth D +8 more
europepmc +1 more source
Langerhans cells shape postnatal oral homeostasis in a mechanical-force-dependent but microbiota and IL17-independent manner. [PDF]
Jaber Y +17 more
europepmc +1 more source
Targeted proteomics reveal histiocytosis‐associated neurodegeneration signatures
Abstract Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), yet its underlying biology and reliable biomarkers remain poorly defined. The aim of this study was to (1) gain insight into neuroimmunological mechanisms governing ND and (2) assess the clinical value of established and novel biomarkers for ND‐LCH.
Egle Kvedaraite +29 more
wiley +1 more source
Mathematical modelling of the role of Langerhans cells in the dynamics of HPV infection. [PDF]
Basir FA +4 more
europepmc +1 more source

