Flow cytometric analysis and sorting of HLA-DR+CD1+ Langerhans cells [PDF]
J. Ashworth, M Kahan, S.M. BREATHNACH
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ABSTRACT Pharmacogenomics remains underutilized in pediatric oncology, despite the existence of evidence‐based guidelines. Implementation of pharmacogenomics‐informed prescribing could improve medication safety and efficacy in pediatric oncology patients, who are at high risk of adverse drug reactions.
Claire Moore+8 more
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Langerhans Cells Directly Interact with Resident T Cells in the Human Epidermis. [PDF]
Oka T+12 more
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TRPV1 activation in human Langerhans cells and T cells inhibits mucosal HIV-1 infection via CGRP-dependent and independent mechanisms. [PDF]
Mariotton J+8 more
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POTASSIUM AND RUBIDIUM PERMEABILITY AND POTASSIUM CONDUCTANCE OF THE β‐CELL MEMBRANE IN MOUSE ISLETS OF LANGERHANS [PDF]
C M Dawson+3 more
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A Novel Polymersome Nanocarrier Promotes Anti‐Tumour Immunity by Improved Priming of CD8 + T Cells
Here, we show that subcutaneous injection of novel artificial cell membrane (ACM) polymersomes loaded with tumour‐specific antigens or peptides, such as OVA, results in efficient anti‐tumour immune responses. In both, a therapeutic and a prophylactic model, we found that ACMs were efficiently taken up by antigen presenting cells, such as dendritic ...
Regine J. Dress+13 more
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Epithelial RANKL Limits Experimental Periodontitis via Langerhans Cells. [PDF]
Netanely Y+15 more
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Abnormal lipid metabolism in epidermal Langerhans cells mediates psoriasis-like dermatitis. [PDF]
Zhang X+12 more
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Darier disease: Current insights and challenges in pathogenesis and management
Darier disease (DD) is characterized by the following: Disrupted Ca2+ gradients, impaired desmosomes, impaired keratinocyte differentiation, type 17 inflammation, DC and LC ↓, Th17 cells ↑. DD treatment: First line: keratinocyte focused and/or anti‐inflammatory. Second line: experimental approaches like specific targeting of the inflammatory infiltrate.
Monika Ettinger+8 more
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Langerhans cells: Central players in the pathophysiology of atopic dermatitis. [PDF]
Pan Y+5 more
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