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Dural involvement in central nervous system langerhans cells histiocytosis (LCH) on FDG PET/CT: Case report and review of CNS manifestations of LCH on PET/CT. [PDF]
Radiol Case RepEddin AS +4 more
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Clonal proliferation of Langerhans cells in Langerhans cell histiocytosis
The Lancet, 1994X-chromosome-inactivation assays can be used to assess clonality. We used such an assay at the human androgen-receptor gene locus in three female patients with histologically proven Langerhans cell histiocytosis. All patients were heterozygous for this locus.
R C, Yu, C, Chu, L, Buluwela, A C, Chu
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Allergy, 1989
The morphological, enzymatical, immunocytochemical and functional properties of Langerhans' cells are briefly reviewed. Langerhans' cells are located mainly in the squamous stratified epithelia, but are also present in the thymus and in superficial lymphnodes.
RUCO, Luigi +2 more
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The morphological, enzymatical, immunocytochemical and functional properties of Langerhans' cells are briefly reviewed. Langerhans' cells are located mainly in the squamous stratified epithelia, but are also present in the thymus and in superficial lymphnodes.
RUCO, Luigi +2 more
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Langerhans' cell histiocytosis cells are activated langerhans' cells
The Journal of Pathology, 1994AbstractLangerhans' cell histiocytosis (LCH) is characterized by the presence of large mononucleated cells, associated with inflammatory cells. The Langerhans' cell (LC) lineage of the mononucleated cells is suggested by the presence of Birbeck granules and the expression of CD1a.
J F, Emile +4 more
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The American Journal of Dermatopathology, 2006
Proliferations of Langerhans cells can be histologically divided into cytologically benign Langerhans cell proliferations, which include the clinical syndromes of Langerhans cell histiocytosis, and cytologically malignant Langerhans cell sarcoma. We report a Langerhans cell sarcoma in a 33-year-old male that arose on the posterior thigh with subsequent
Tammie, Ferringer +2 more
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Proliferations of Langerhans cells can be histologically divided into cytologically benign Langerhans cell proliferations, which include the clinical syndromes of Langerhans cell histiocytosis, and cytologically malignant Langerhans cell sarcoma. We report a Langerhans cell sarcoma in a 33-year-old male that arose on the posterior thigh with subsequent
Tammie, Ferringer +2 more
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Journal of Cutaneous Medicine and Surgery, 2012
Background: The cutaneous presentation of Langerhans cell histiocytosis (LCH) is very rare and can be highly variable among individuals, which can often lead to a delay in diagnosis. Objective: To discuss a case report and literature review of important clinical indicators, histology, diagnosis, evaluation, and treatment guidelines.
Ligaya, Park +2 more
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Background: The cutaneous presentation of Langerhans cell histiocytosis (LCH) is very rare and can be highly variable among individuals, which can often lead to a delay in diagnosis. Objective: To discuss a case report and literature review of important clinical indicators, histology, diagnosis, evaluation, and treatment guidelines.
Ligaya, Park +2 more
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Skeletal Radiology, 2006
Langerhans cell histiocytosis (LCH) is a complex disease entity comprised of three distinct clinical syndromes that demonstrate indistinguishable histology. These syndromes are: eosinophilic granuloma, which is predominantly osseous or pulmonary; Hand-Schûller-Christian's disease, which involves multiple organ systems and, most typically, the skull ...
Kevin Bradford, Hoover +2 more
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Langerhans cell histiocytosis (LCH) is a complex disease entity comprised of three distinct clinical syndromes that demonstrate indistinguishable histology. These syndromes are: eosinophilic granuloma, which is predominantly osseous or pulmonary; Hand-Schûller-Christian's disease, which involves multiple organ systems and, most typically, the skull ...
Kevin Bradford, Hoover +2 more
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Archives of Disease in Childhood, 2009
Langerhans cell histiocytosis is a rare disease. Depending on which organs are involved, the disease may prove rapidly fatal, develop a chronic reactivating but therapy-responsive pattern or resolve spontaneously. Understanding of the pathology of the disease is progressing rapidly, and while clinical trials of standard chemotherapy agents continue, it
K, Windebank, V, Nanduri
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Langerhans cell histiocytosis is a rare disease. Depending on which organs are involved, the disease may prove rapidly fatal, develop a chronic reactivating but therapy-responsive pattern or resolve spontaneously. Understanding of the pathology of the disease is progressing rapidly, and while clinical trials of standard chemotherapy agents continue, it
K, Windebank, V, Nanduri
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Journal of the American Academy of Dermatology, 1982
Langerhans cells (LCs) function as the most peripheral outpost of the immune system. Although first identified in the skin, these cells probably originate in the bone marrow and migrate actively between the epidermis and the lymph nodes. They appear to play a critical role in immune surveillance and the development of contact allergy. The importance of
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Langerhans cells (LCs) function as the most peripheral outpost of the immune system. Although first identified in the skin, these cells probably originate in the bone marrow and migrate actively between the epidermis and the lymph nodes. They appear to play a critical role in immune surveillance and the development of contact allergy. The importance of
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Langerhans' cell histiocytosis
The Lancet, 2005A 38-year-old woman complained of persistent chest pain. A plain radiograph showed an irregularity on the sternum, and bone-scan showed uptake only in that area. Thoracic-abdominal CT showed an osteolytic lesion of the sternum (figure) without any other signs of neoplasia.
N. Fazio +4 more
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