Results 231 to 240 of about 4,466,969 (285)

The Spatial and Temporal Repeatability of Genomic Responses to Natural Selection as Demonstrated in Stickleback Populations Experiencing Highly Dynamic Environments

open access: yesMolecular Ecology, Volume 35, Issue 17, September 2026.
ABSTRACT The evolution of genotypic parallelism under shared environmental conditions provides strong evidence for the role of natural selection. However, analyses typically examine genomic signatures of selection long after the putative selection event and only assess the repeatability of responses across spatial population replicates.
Mary Kathleen Hickox   +5 more
wiley   +1 more source

Intra‐Islet Paracrine Regulation of Glucagon Secretion During Hypoglycemia, Euglycemia, and Hyperglycemia

open access: yesAnnals of the New York Academy of Sciences, Volume 1563, Issue 1, September 2026.
Glucagon, a counterregulatory hormone released from pancreatic α‐cells, maintains glucose homeostasis by acting as a protective barrier against hypoglycemia and an amplifier of insulin release when glucose levels rise with feeding. In the body, glucagon secretion is regulated by circulating glucose levels, with elevations in amino acids and via other ...
Samaneh Fatehi   +2 more
wiley   +1 more source

Stathmin‐2 mediates paracrine hormone regulation of glucagon through lysosomal trafficking in αTC1‐6 cells

open access: yesThe Journal of Physiology, Volume 604, Issue 17, Page 7225-7245, 1 September 2026.
Abstract figure legend Paracrine regulation of glucagon involves Stathmin2‐mediated trafficking of glucagon through lysosomal transport. Glucagon secretion is regulated by the paracrine hormones insulin and somatostatin. We postulate that insulin enhances lysosomal transport of glucagon away from sites of exocytosis, and somatostatin functions in the ...
Nelson Chang   +2 more
wiley   +1 more source

Novel BRAF fusion in Erdheim–Chester disease with pulmonary manifestations: Importance of RNA‐based testing and response to MEK inhibition

open access: yes
Histopathology, Volume 89, Issue 3, Page 558-561, September 2026.
Igor Odintsov   +5 more
wiley   +1 more source

The Langerhans' cells*

open access: yesAllergy, 1989
The morphological, enzymatical, immunocytochemical and functional properties of Langerhans' cells are briefly reviewed. Langerhans' cells are located mainly in the squamous stratified epithelia, but are also present in the thymus and in superficial lymphnodes.
RUCO, Luigi   +2 more
openaire   +4 more sources

Biology of Langerhans Cells and Langerhans Cell Histiocytosis

International Review of Cytology, 2006
Langerhans cells (LC) are epidermal dendritic cells (DC). They play an important role in the initiation of immune responses through antigen uptake, processing, and presentation to T cells. Langerhans cell histiocytosis (LCH) is a rare disease in which accumulation of cells with LC characteristics (LCH cells) occur. LCH lesions are further characterized
R J Arceci, R M Egeler
exaly   +3 more sources

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