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ABSTRACT The evolution of genotypic parallelism under shared environmental conditions provides strong evidence for the role of natural selection. However, analyses typically examine genomic signatures of selection long after the putative selection event and only assess the repeatability of responses across spatial population replicates.
Mary Kathleen Hickox +5 more
wiley +1 more source
The role of the epithelial sentinels, Langerhans cells and γδT cells, in oral squamous cell carcinoma. [PDF]
Hovav AH, Wilensky A.
europepmc +1 more source
Glucagon, a counterregulatory hormone released from pancreatic α‐cells, maintains glucose homeostasis by acting as a protective barrier against hypoglycemia and an amplifier of insulin release when glucose levels rise with feeding. In the body, glucagon secretion is regulated by circulating glucose levels, with elevations in amino acids and via other ...
Samaneh Fatehi +2 more
wiley +1 more source
Abstract figure legend Paracrine regulation of glucagon involves Stathmin2‐mediated trafficking of glucagon through lysosomal transport. Glucagon secretion is regulated by the paracrine hormones insulin and somatostatin. We postulate that insulin enhances lysosomal transport of glucagon away from sites of exocytosis, and somatostatin functions in the ...
Nelson Chang +2 more
wiley +1 more source
Major Histocompatibility Complex II Expression on Oral Langerhans Cells Differentially Regulates Mucosal CD4 and CD8 T Cells. [PDF]
Fischer LA +2 more
europepmc +1 more source
MHC-II presentation by oral Langerhans cells impacts intraepithelial Tc17 abundance and Candida albicans oral infection via CD4 T cells. [PDF]
Bittner-Eddy PD +3 more
europepmc +1 more source
Histopathology, Volume 89, Issue 3, Page 558-561, September 2026.
Igor Odintsov +5 more
wiley +1 more source
Dural involvement in central nervous system langerhans cells histiocytosis (LCH) on FDG PET/CT: Case report and review of CNS manifestations of LCH on PET/CT. [PDF]
Eddin AS +4 more
europepmc +1 more source
The morphological, enzymatical, immunocytochemical and functional properties of Langerhans' cells are briefly reviewed. Langerhans' cells are located mainly in the squamous stratified epithelia, but are also present in the thymus and in superficial lymphnodes.
RUCO, Luigi +2 more
openaire +4 more sources
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Biology of Langerhans Cells and Langerhans Cell Histiocytosis
International Review of Cytology, 2006Langerhans cells (LC) are epidermal dendritic cells (DC). They play an important role in the initiation of immune responses through antigen uptake, processing, and presentation to T cells. Langerhans cell histiocytosis (LCH) is a rare disease in which accumulation of cells with LC characteristics (LCH cells) occur. LCH lesions are further characterized
R J Arceci, R M Egeler
exaly +3 more sources

