Results 91 to 100 of about 13,215,280 (371)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Indoor and outdoor particulate matter concentrations on the Mpumalanga highveld – A case study

open access: yesClean Air Journal, 2015
The household combustion of solid fuels, for the purpose of heating and cooking, is an activity practiced by many people in South Africa. Air pollution caused by the combustion of solid fuels in households has a significant influence on public health ...
B Wernecke   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Variation of Indoor Particulate Matter Concentrations and Association with Indoor/Outdoor Temperature: A Case Study in Rural Limpopo, South Africa

open access: yesAtmosphere, 2018
There is still a pressing concern regarding the causes of poor indoor air quality and the consequent effects on health, because people spend a considerable amount of time indoors.
Thandi Kapwata   +3 more
doaj   +1 more source

THE LEARNERS’ ATTITUDE TOWARD JAVANESE LANGUAGE SUBJECT AS ONE OF JAVANESE’S LANGUAGE MAINTENANCE EFFORT [PDF]

open access: yes, 2012
As a multilingual country, language maintenance is important to prevent the local language or varieties from being perished. Javanese language subject at school is one of the languagemaintenance efforts from the government and this paper discusses about
Seinsiani , Izzati Gemi
core  

Natural language processing [PDF]

open access: yes, 2003
Beginning with the basic issues of NLP, this chapter aims to chart the major research activities in this area since the last ARIST Chapter in 1996 (Haas, 1996), including: (i) natural language text processing systems - text summarization, information ...
Adams   +101 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

WILL JAVANESE LANGUAGE BECOME EXTINCT? [PDF]

open access: yes, 2015
Indonesia has so many ethnic groups whose languages are different from each other. There are some big ethnic groups; Javanese, Sundanese, and etc. Here, in this case, the writer only focuses on one of Indonesia’s ethnics and languages that is Javanese.
Permanasari, Pradnya
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Ten Steps to a Conducting Large, Multi-site, Longitudinal Investigation of Language and Reading in Young Children

open access: yesFrontiers in Psychology, 2016
Purpose: This paper describes methodological procedures involving execution of a large-scale, multi-site longitudinal study of language and reading comprehension in young children.
Language and Reading Research eConsortium   +2 more
doaj   +1 more source

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