Results 61 to 70 of about 457,462 (314)

What is the Role and Nature of Language and Language Development? [PDF]

open access: yes, 2020
In this paper, the role and nature of language and language development will be discussed. Research and theory in second language acquisition has demonstrated that (i) language is an abstract, implicit and complex system.
Alessandro Benati, Benati, A
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Multi-Talker Speech Promotes Greater Knowledge-Based Spoken Mandarin Word Recognition in First and Second Language Listeners

open access: yesFrontiers in Psychology, 2020
Spoken word recognition involves a perceptual tradeoff between the reliance on the incoming acoustic signal and knowledge about likely sound categories and their co-occurrences as words.
Seth Wiener, Chao-Yang Lee
doaj   +1 more source

Identifying formulas in first language acquisition

open access: yes, 2013
With the increase in interest in formulas, or apparently non-productive utterances in children's speech, a range of definitions has emerged and sometimes conflicting criteria have been proposed for their identification.
Hickey, Tina
core   +1 more source

Directives in Finnish language acquisition

open access: yes, 2021
Modal expressions in child speech are examined from the point of agent-oriented modalityPeer ...
Laalo, Klaus, Klaus Laalo
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Effects of input elaboration and enhancement on second language vocabulary acquisition through reading by Korean learners of English [PDF]

open access: yes, 2003
The present study investigates the effects of lexical elaboration and typographical enhancement on the acquisition of second language (L2) vocabulary through reading by 297 Korean learners of Freshman English.
Kim, Youngkyu
core  

Language Acquisition and Connectionism

open access: yesLanguage and Cognitive Processes, 1998
What aspects of connectionist models guarantee cognitive and linguistic outcomes? A range of computational and input assumptions are explored and the general approaches and implications of the accompanying articles are briefly reviewed.
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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