Results 71 to 80 of about 1,514,853 (347)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Cross-Linguistic Universals in Reading Acquisition with Applications to English-Language Learners with Reading Disabilities [PDF]

open access: yes, 2009
There is a considerable gap in English reading achievement between English-language learners and native speakers in the United States. Differentiation of whether English language learners’ struggles are symptomatic of reading disability or related to ...
Gorman, Brenda K.
core   +1 more source

'Children are just lingual': The development of phonology in British Sign Language (BSL) [PDF]

open access: yes, 2006
This paper explores three universal tendencies in spoken language acquisition: consonant and vowel harmony, cluster reduction and systemic simplification, using a corpus of 1018 signs from a single child exposed to British Sign Language from birth. Child
Morgan, G.
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Towards a Unified Model of Language Acquisition [PDF]

open access: yes, 2007
In this theoretical paper, we first review and rebut standard criticisms against distributional approaches to language acquisition. We then present two closely-related models that use distributional analysis.
Freudenthal, D, Gobet, F, Pine, J M
core  

The road to language learning is not entirely iconic: Iconicity, neighborhood density, and frequency facilitate sign language acquisition [PDF]

open access: yes, 2017
Iconic mappings between words and their meanings are far more prevalent than once estimated, and seem to support children’s acquisition of new words, spoken or signed.
Caselli, Naomi, Pyers, Jennie
core   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Memory-Based Lexical Acquisition and Processing [PDF]

open access: yes, 1994
Current approaches to computational lexicology in language technology are knowledge-based (competence-oriented) and try to abstract away from specific formalisms, domains, and applications.
Daelemans, Walter
core   +7 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

THE CHILD AND THE WORLD: How Children acquire Language [PDF]

open access: yes, 2005
HOW CHILDREN ACQUIRE LANGUAGE Over the last few decades research into child language acquisition has been revolutionized by the use of ingenious new techniques which allow one to investigate what in fact infants (that is children not yet able to speak)
Allott, Robin
core  

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