Results 51 to 60 of about 1,437,018 (263)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Criticism and correction of some verses from the sixth book of Shahnameh published by Khaleghi Mutlaq [PDF]

پژوهشهای نسخه شناسی و تصحیح متون
Jalal Khaleghi mutlaq has made an exhausting effort in correcting Ferdowsi's Shahnameh, but by recording all the altered versions in the footnotes he has exposed the critical text of the Shahnameh to the criticism and assessment of researchers in the ...
dariush ghale ghobadi, teymoor malmir
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Examining language attitudes and use: A survey of Indonesian university students’ loyalty to their ethnic languages

Indonesian Journal of Applied Linguistics
Currently, a large number of ethnic languages worldwide are losing their vitality and popularity due to globalization and the influence of dominant languages such as English and Indonesian.
Dingding Haerudin, Ruswan Dallyono, Usep Kuswari, Dedi Koswara   +3 more
doaj   +1 more source

The Correction of Two Mistakes in the Biography of Mohammad Hossein Hosseini-e Shirazi, Poet and Mystic in Qajar Era [PDF]

تاریخ ادبیات
IntroductionThe effort of researchers in biography writing has led to a better knowledge of poets’ lives and works, but sometimes there are mistakes in the information. Therefore, it is necessary to review them to create a secure foundation by correcting
Masume Sadeqi, Mahin Panahi, Mahdi Nikmanesh   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Critical Analysis of Deficiencies in the Edition of Hilali Joghata'i's Divan and Discovery of Newly Found Poems [PDF]

متن شناسی ادب فارسی
Hilali Joghata'i is a prominent poet of the 9th and 10th centuries AH, contemporary with the Timurian and Safavid eras. His extant divan consists mainly of ghazals, but also includes odes, rubaiyats, and pieces.
Amin Yaghoubi, Mehdi Dehghan
doaj   +1 more source